A multi-agent approach for biological models cooperation
Résumé
Several formalisms and approaches exist for mathematically modeling biological processes. The same process can be modelled using different formalisms. Each obtained model could be considered as a “point of view” of the biological model, or an “approach” for studying in silico the biological process. It is therefore interesting to be able to make cooperating different mathematical modeling of the same biological process, in order to display behaviors that could not be seen in single model. For this purpose, we propose a multi-agent approach for implementing this cooperation. We have experimented our approach on a well known biological example, the bacteriophage lambda. The bacteriophage lambda is a virus which infects Escherichia Coli bacteria. It is considered as a very simple organism and has been greatly studied. In this abstract, we show with a small example, how a deteministic model and a stochastic model of the genetic switch of the phage, cooperate in order to deal with rare chemical reactions and frequent ones according to their relevance.
Domaines
Bio-informatique [q-bio.QM]Origine | Fichiers produits par l'(les) auteur(s) |
---|