The Mohr-Coulomb criterion is widely used in geosciences and solid mechanics to relate the state of stress at failure to the observed orientation of the resulting faults. This relation is based on the assumption that macroscopic failure takes place along the plane that maximizes the Coulomb stress. Here, this hypothesis is assessed by simulating compressive tests on an elasto-damageable material that follows the Mohr-Coulomb criterion at the mesoscopic scale. We find that the macroscopic fault orientation is not given by the Mohr-Coulomb criterion. Instead, for a weakly disordered material, it corresponds to the most unstable mode of damage growth, which we determine through a linear stability analysis of its homogeneously damaged state. Our study reveals that compressive failure emerges from the coalescence of damaged clusters within the material and that this collective process is suitably described at the continuum scale by introducing an elastic kernel that describes the interactions between these clusters.