Closed-loop cardiovascular system model and partial hepatectomy simulation

Chloé Audebert 1 Petru Bucur 2, 3 Eric Vibert 3 Jean-Frédéric Gerbeau 1 Irene Vignon-Clementel 1
1 REO - Numerical simulation of biological flows
LJLL - Laboratoire Jacques-Louis Lions, Inria Paris-Rocquencourt, UPMC - Université Pierre et Marie Curie - Paris 6
Abstract : The present work aims at developing a mathematical model in order to reproduce hemodynamics changes due to liver surgeries. First, a 0D closed-loop model is developed, to simulate hepatectomy and compute post-operative average values. Due to the closed loop, the surgery impact both on and from the whole circulation can be captured, including bleeding and infusion. Then, a one-dimensional artery model is implemented to improve the closed-loop model and simulate better the changes in arterial waveforms due to surgery.
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Chloé Audebert, Petru Bucur, Eric Vibert, Jean-Frédéric Gerbeau, Irene Vignon-Clementel. Closed-loop cardiovascular system model and partial hepatectomy simulation. 4th International Conference on Computational and Mathematical Biomedical Engineering - CMBE2015, Jun 2015, Cachan, France. ⟨hal-01240144⟩

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