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Pathological calcifications: a medical diagnosis based on their physicochemical properties Dominique Bazin 9ffe18cfaeb3d707247d0d3061b733f1 universite-paris-saclay.fr dominique-bazin 748934 54455-748934 http://www.researcherid.com/rid/C-6306-2014 https://orcid.org/0000-0002-5112-9061 https://www.idref.fr/167327941 http://www.researcherid.com/rid/http://www.researcherid.com/rid/C-6306-2014 https://viaf.org/viaf/177974350 http://isni.org/isni/000000038540601X Jean-Philippe Haymann ee431573955a3c1c6001bf97f78fe9f7 tnn.aphp.fr 1148098 827399-1148098 https://www.idref.fr/069847894 Letavernier Emmanuel d794aedeec005fa7a999044e3d004e87 tnn.aphp.fr 989574 827398-989574 https://orcid.org/0000-0002-6053-8975 https://www.idref.fr/083898557 Julie Rode 829544-0 Michel Daudon 36a0dce70c66afb37bc831d1906d649f tnn.aphp.fr 1148101 779547-1148101 https://orcid.org/0000-0001-9844-9823 HAL SU Administrateur 1431aca8052643840c2b6a4d1a99b1e4 sorbonne-universite.fr 2014-05-26 12:48:17 2025-12-08 14:42:12 2014-05-26 13:05:23 2014-02 2014-05-26 contributor HAL SU Administrateur 1431aca8052643840c2b6a4d1a99b1e4 sorbonne-universite.fr CCSD hal-00996294 https://hal.sorbonne-universite.fr/hal-00996294 bazin:hal-00996294 <i>La Presse Médicale</i>, 2014, 43 (2), pp.135-48. <a target="_blank" href="https://dx.doi.org/10.1016/j.lpm.2013.02.333">⟨10.1016/j.lpm.2013.02.333⟩</a> La Presse Médicale, 2014, 43 (2), pp.135-48. ⟨10.1016/j.lpm.2013.02.333⟩ HAL Authorization Université Pierre et Marie Curie CNRS - Centre national de la recherche scientifique Collège de France Université Paris Sud - Paris XI AP-HP Laboratoire de Chimie de la Matière Condensée de Paris Institut de Chimie du CNRS Spectroscopie, Modélisation, Interfaces pour L'Environnement et la Santé Université Paris sciences et lettres Université Paris-Saclay Université Paris Sud pour Paris Saclay UPMC Pôle 2 Sorbonne Université SORBONNE université <2018 Faculté de Santé de Sorbonne Université Faculté des Sciences de Sorbonne Université Médecine - Sorbonne Université Collège de France - PSL Sorbonne Université - Texte Intégral Graduate School Physique Laboratoire de Physique des Solides d'Orsay Alliance Sorbonne Université Laboratoire de Psychologie Sociale : contextes et régulation TEST2-HALCNRS UFR de Chimie de Sorbonne-Université International No Yes Pathological calcifications: a medical diagnosis based on their physicochemical properties Dominique Bazin 9ffe18cfaeb3d707247d0d3061b733f1 universite-paris-saclay.fr dominique-bazin 748934 54455-748934 http://www.researcherid.com/rid/C-6306-2014 https://orcid.org/0000-0002-5112-9061 https://www.idref.fr/167327941 http://www.researcherid.com/rid/http://www.researcherid.com/rid/C-6306-2014 https://viaf.org/viaf/177974350 http://isni.org/isni/000000038540601X Jean-Philippe Haymann ee431573955a3c1c6001bf97f78fe9f7 tnn.aphp.fr 1148098 827399-1148098 https://www.idref.fr/069847894 Letavernier Emmanuel d794aedeec005fa7a999044e3d004e87 tnn.aphp.fr 989574 827398-989574 https://orcid.org/0000-0002-6053-8975 https://www.idref.fr/083898557 Julie Rode 829544-0 Michel Daudon 36a0dce70c66afb37bc831d1906d649f tnn.aphp.fr 1148101 779547-1148101 https://orcid.org/0000-0001-9844-9823 21447 0755-4982 2213-0276 La Presse Médicale Elsevier Masson [1983-....] 43 2 135-48 2014-02 2013-08-13 10.1016/j.lpm.2013.02.333 23953927 French Apatites Calcinosis Humans Physicochemical Phenomena Life Sciences [q-bio]/Human health and pathology Journal articles Journal articles Journal articles

This paper gathers different investigations dedicated to pathological calcifications made of apatite in order to define the structural characteristics, which display a clinical significance. Such approach helps the clinician to define the characterisation tools, which have to be combined to obtain such structural characteristics in order to establish a possible relationship between the structural characteristics of the pathological calcifications and the disease. The fact that it is now possible to perform such experiments at the subcellular scale gives new opportunities for a large number of diseases associated to pathological calcification. Moreover, new diagnostic tools based on these characterisation techniques, quite sensitive to analyze microcrystals, can be defined.

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