Mimic therapeutic actions against keloid by thermostatted kinetic theory methods - Sorbonne Université Access content directly
Journal Articles The European Physical Journal Plus Year : 2015

Mimic therapeutic actions against keloid by thermostatted kinetic theory methods

Abstract

This paper deals with the modeling of a wound-healing disease under a therapeutic action by employing the methods of the thermostatted kinetic theory for active particles. In particular, in order to test therapeutic actions against keloid formation and the possible development of a cancer, an external force field coupled to a Gaussian thermostat is introduced into a mathematical model recently proposed. Specifically the model depicts the competition of the immune system cells with a virus, the mutated fibroblast cells, and the cancer cells. Employing a computational analysis, the effects of three different external forces mimic therapeutic actions are analyzed: A vaccine for the virus, the PUVA therapy for the keloid and a vaccine for the cancer. The results are in agreement with the evidence that the sole action of the immune system is not sufficient to obtain a total depletion of keloid thus requiring the definition of a therapy. Further refinements and developments of the model are also discussed in the paper.
Fichier principal
Vignette du fichier
Bianca_2015_Mimic_therapeutic.pdf (5.31 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-01190908 , version 1 (01-09-2015)

Identifiers

Cite

Carlo Bianca, Julien Riposo. Mimic therapeutic actions against keloid by thermostatted kinetic theory methods. The European Physical Journal Plus, 2015, 130 (8), pp.1-14. ⟨10.1140/epjp/i2015-15159-4⟩. ⟨hal-01190908⟩
35 View
139 Download

Altmetric

Share

Gmail Facebook X LinkedIn More