Polyethylene glycol Gold-Nanoparticles: Facile Nanostructuration of Doxorubicin and its complex with DNA molecules for SERS detection - Sorbonne Université Accéder directement au contenu
Article Dans Une Revue Chemical Physics Letters Année : 2016

Polyethylene glycol Gold-Nanoparticles: Facile Nanostructuration of Doxorubicin and its complex with DNA molecules for SERS detection

Résumé

We report the synthesis of dicarboxylic acid-terminated polyethylene-glycol (PEG)-gold nanoparticles by a simple one-step method, and their further use to form nanostructured surfaces for biomolecule immobilization. The synthesized nano-scale particles were conjugated with probe/target oligonucleotides in order to evaluate intercalation phenomenon in the presence of doxorubicin drug via Surface Enhanced Raman Spectroscopy (SERS) analysis.

Domaines

Chimie
Fichier principal
Vignette du fichier
Spadavecchia_Polyethylene_glycol.pdf (1.75 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-01196383 , version 1 (09-09-2015)

Identifiants

Citer

Jolanda Spadavecchia, Ramesh Perumal, Sandra Casale, Jean-Marc Krafft, Christophe Methivier, et al.. Polyethylene glycol Gold-Nanoparticles: Facile Nanostructuration of Doxorubicin and its complex with DNA molecules for SERS detection. Chemical Physics Letters, 2016, 648, pp.182-188. ⟨10.1016/j.cplett.2015.08.038⟩. ⟨hal-01196383⟩
178 Consultations
435 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More