Polyethylene glycol Gold-Nanoparticles: Facile Nanostructuration of Doxorubicin and its complex with DNA molecules for SERS detection
Résumé
We report the synthesis of dicarboxylic acid-terminated polyethylene-glycol (PEG)-gold nanoparticles by a simple one-step method, and their further use to form nanostructured surfaces for biomolecule immobilization. The synthesized nano-scale particles were conjugated with probe/target oligonucleotides in order to evaluate intercalation phenomenon in the presence of doxorubicin drug via Surface Enhanced Raman Spectroscopy (SERS) analysis.
Domaines
Chimie
Origine : Fichiers produits par l'(les) auteur(s)
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