S. Dallas and L. Bonewald, Dynamics of the transition from osteoblast to osteocyte, Annals of the New York Academy of Sciences, vol.189, issue.suppl 1, pp.437-480, 2010.
DOI : 10.1111/j.1749-6632.2009.05246.x

S. Dallas, M. Prideaux, and L. Bonewald, The Osteocyte: An Endocrine Cell ??? and More, Endocrine Reviews, vol.34, issue.5, pp.658-90, 2013.
DOI : 10.1210/er.2012-1026

T. Franz-odendaal, B. Hall, and P. Witten, Buried alive: How osteoblasts become osteocytes, Developmental Dynamics, vol.113, issue.31, pp.176-90, 2006.
DOI : 10.1002/dvdy.20603

M. Hirao, J. Hashimoto, N. Yamasaki, W. Ando, H. Tsuboi et al., Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes, Journal of Bone and Mineral Metabolism, vol.10, issue.Suppl 1, pp.266-76, 2007.
DOI : 10.1007/s00774-007-0765-9

Y. Yan, Y. Gong, Y. Guo, Q. Lv, C. Guo et al., Mechanical Strain Regulates Osteoblast Proliferation through Integrin-Mediated ERK Activation, PLoS ONE, vol.24, issue.52, p.35709, 2012.
DOI : 10.1371/journal.pone.0035709.s006

Y. Guo, C. Zhang, Q. Zeng, R. Li, L. Liu et al., Mechanical strain promotes osteoblast ECM formation and improves its osteoinductive potential, BioMedical Engineering OnLine, vol.11, issue.1, p.80, 2012.
DOI : 10.1186/1475-925X-11-80

O. Akhouayri, M. Lafage-proust, A. Rattner, N. Laroche, A. Caillot-augusseau et al., Effects of static or dynamic mechanical stresses on osteoblast phenotype expression in three-dimensional contractile collagen gels, Journal of Cellular Biochemistry, vol.22, issue.2, pp.217-247, 1999.
DOI : 10.1002/(SICI)1097-4644(20000201)76:2<217::AID-JCB6>3.0.CO;2-K

J. Jokinen, E. Dadu, P. Nykvist, J. Kaepylae, D. White et al., Integrin-mediated Cell Adhesion to Type I Collagen Fibrils, Journal of Biological Chemistry, vol.279, issue.30, pp.31956-63, 2004.
DOI : 10.1074/jbc.M401409200

D. White, S. Puranen, M. Johnson, and J. Heino, The collagen receptor subfamily of the integrins, The International Journal of Biochemistry & Cell Biology, vol.36, issue.8, pp.1405-1415, 2004.
DOI : 10.1016/j.biocel.2003.08.016

S. Tsai, C. Chen, P. Chen, and F. Hsu, Influence of topography of nanofibrils of threedimensional collagen gel beads on the phenotype, proliferation, and maturation of osteoblasts, J Biomed Mater Res, Part A, vol.91, pp.985-93, 2008.

P. Buxton, M. Bitar, K. Gellynck, M. Parkar, R. Brown et al., Dense collagen matrix accelerates osteogenic differentiation and rescues the apoptotic response to MMP inhibition, Bone, vol.43, issue.2, pp.377-85, 2008.
DOI : 10.1016/j.bone.2008.03.028

J. Silvent, N. Nassif, C. Helary, T. Azais, J. Sire et al., Collagen Osteoid-Like Model Allows Kinetic Gene Expression Studies of Non-Collagenous Proteins in Relation with Mineral Development to Understand Bone Biomineralization, PLoS ONE, vol.23, issue.2, p.57344, 2013.
DOI : 10.1371/journal.pone.0057344.s004

URL : https://hal.archives-ouvertes.fr/hal-01142641

G. Guille, M. Helary, C. Vigier, S. Nassif, and N. , Dense fibrillar collagen matrices for tissue repair, Soft Matter, vol.16, issue.20, pp.4963-4970, 2010.
DOI : 10.1039/c0sm00260g

URL : https://hal.archives-ouvertes.fr/hal-00525304

K. Elias, R. Price, and T. Webster, Enhanced functions of osteoblasts on nanometer diameter carbon fibers, Biomaterials, vol.23, issue.15, pp.3279-87, 2002.
DOI : 10.1016/S0142-9612(02)00087-X

S. Vigier, C. Helary, O. Fromigue, P. Marie, and M. Giraud-guille, Collagen supramolecular and suprafibrillar organizations on osteoblasts long-term behavior: Benefits for bone healing materials, Journal of Biomedical Materials Research Part A, vol.376, pp.556-67, 2010.
DOI : 10.1002/jbm.a.32717

Y. Wang, E. Von, F. Fernandes, S. Cassaignon, M. Selmane et al., Water-mediated structuring of bone apatite, Nature Materials, vol.84, issue.311, pp.1144-53, 2013.
DOI : 10.1038/nmat3787

URL : https://hal.archives-ouvertes.fr/hal-01289769

Y. Wang, T. Azais, R. M. Vallee, A. Catania, C. Legriel et al., The predominant role of collagen??in the nucleation, growth, structure??and orientation??of??bone apatite, Nature Materials, vol.41, issue.8, pp.724-757, 2012.
DOI : 10.1038/nmat3362

URL : https://hal.archives-ouvertes.fr/hal-01461430

F. Gobeaux, E. Belamie, G. Mosser, P. Davidson, P. Panine et al., Cooperative Ordering of Collagen Triple Helices in the Dense State, Langmuir, vol.23, issue.11, pp.6411-6418, 2007.
DOI : 10.1021/la070093z

URL : https://hal.archives-ouvertes.fr/hal-00184115

C. Helary, A. Foucault-bertaud, G. Godeau, B. Coulomb, and M. Guille, Fibroblast populated dense collagen matrices: cell migration, cell density and metalloproteinases expression, Biomaterials, vol.26, issue.13, pp.1533-1576, 2005.
DOI : 10.1016/j.biomaterials.2004.05.016

L. Besseau, B. Coulomb, C. Lebreton-decoster, and M. Giraud-guille, Production of ordered collagen matrices for three-dimensional cell culture, Biomaterials, vol.23, issue.1, pp.27-36, 2001.
DOI : 10.1016/S0142-9612(01)00075-8

S. Rhee and J. Tanaka, Hydroxyapatite formation on cellulose cloth induced by citric acid, Journal of Materials Science: Materials in Medicine, vol.11, issue.7, pp.449-52, 2000.
DOI : 10.1023/A:1008992009826

N. Nassif, F. Martineau, O. Syzgantseva, F. Gobeaux, M. Willinger et al., Inspired Conditions to Synthesize Biomimetic Hydroxyapatite, Vivo Inspired Conditions to Synthesize Biomimetic Hydroxyapatite, pp.3653-63, 2010.
DOI : 10.1021/cm903596q

M. Coelho, A. Cabral, and M. Fernandes, Human bone cell cultures in biocompatibility testing. Part I: osteoblastic differentiation of serially passaged human bone marrow cells cultured in ??-MEM and in DMEM, Biomaterials, vol.21, issue.11, pp.1087-94, 2000.
DOI : 10.1016/S0142-9612(99)00284-7

M. Coelho and M. Fernandes, Human bone cell cultures in biocompatibility testing. Part II: effect of ascorbic acid, ??-glycerophosphate and dexamethasone on osteoblastic differentiation, Biomaterials, vol.21, issue.11, pp.1095-102, 2000.
DOI : 10.1016/S0142-9612(99)00192-1

R. Barber, D. Harmer, R. Coleman, and B. Clark, GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues, Physiological Genomics, vol.21, issue.3, pp.389-95, 2005.
DOI : 10.1152/physiolgenomics.00025.2005

M. Pfaffl, A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Research, vol.29, issue.9, p.45, 2001.
DOI : 10.1093/nar/29.9.e45

M. Glimcher, Bone: Nature of the Calcium Phosphate Crystals and Cellular, Structural, and Physical Chemical Mechanisms in Their Formation, Reviews in Mineralogy and Geochemistry, vol.64, issue.1, pp.223-82, 2006.
DOI : 10.2138/rmg.2006.64.8

Y. Wang, V. Euw, S. Laurent, G. Crevant, C. Bonhomme-coury et al., Impact of collagen confinement vs. ionic substitutions on the local disorder in bone and biomimetic apatites, Mater. Horiz., vol.9, issue.2, pp.224-255, 2014.
DOI : 10.1038/NMAT3787

URL : https://hal.archives-ouvertes.fr/hal-01275062

E. Gentleman, R. Swain, N. Evans, S. Boonrungsiman, G. Jell et al., Comparative materials differences revealed in engineered bone as a function of cell-specific differentiation, Nature Materials, vol.92, issue.9, pp.763-70, 2009.
DOI : 10.1038/nmat2505

F. Gobeaux, G. Mosser, A. Anglo, P. Panine, P. Davidson et al., Fibrillogenesis in Dense Collagen Solutions: A Physicochemical Study, Journal of Molecular Biology, vol.376, issue.5, pp.1509-1531, 2008.
DOI : 10.1016/j.jmb.2007.12.047

URL : https://hal.archives-ouvertes.fr/hal-00277303

M. Stahle-baeckdahl, B. Sandstedt, K. Bruce, A. Lindahl, M. Jimenez et al., Collagenase-3 (MMP-13) is expressed during human fetal ossification and re-expressed in postnatal bone remodeling and in rheumatoid arthritis, Lab Invest, vol.76, pp.717-745, 1997.

H. Harris, The human alkaline phosphatases: What we know and what we don't know, Clinica Chimica Acta, vol.186, issue.2, pp.133-50, 1990.
DOI : 10.1016/0009-8981(90)90031-M

P. Rowe, D. Zoysa, P. Dong, R. Wang, H. White et al., MEPE, a New Gene Expressed in Bone Marrow and Tumors Causing Osteomalacia, Genomics, vol.67, issue.1, pp.54-68, 2000.
DOI : 10.1006/geno.2000.6235

T. Hayashibara, T. Hiraga, Y. B. Nomizu, M. Kumagai, Y. Nishimura et al., A Synthetic Peptide Fragment of Human MEPE Stimulates New Bone Formation In Vitro and In Vivo, Journal of Bone and Mineral Research, vol.177, issue.3, pp.455-62, 2004.
DOI : 10.1359/JBMR.0301263

B. Ganss, R. Kim, and J. Sodek, Bone Sialoprotein, Critical Reviews in Oral Biology & Medicine, vol.10, issue.1, pp.79-98, 1999.
DOI : 10.1177/10454411990100010401

F. Boukhechba, T. Balaguer, J. Michiels, K. Ackermann, D. Quincey et al., Human Primary Osteocyte Differentiation in a 3D Culture System, Journal of Bone and Mineral Research, vol.24, issue.11, pp.1927-1962, 2009.
DOI : 10.1359/jbmr.090517

A. Perrier, V. Dumas, M. Linossier, C. Fournier, P. Jurdic et al., Apatite content of collagen materials dose-dependently increases pre-osteoblastic cell deposition of a cement line-like matrix, Bone, vol.47, issue.1, pp.23-33, 2010.
DOI : 10.1016/j.bone.2010.03.010

F. Knopf, C. Hammond, A. Chekuru, T. Kurth, S. Hans et al., Bone Regenerates via Dedifferentiation of Osteoblasts in the Zebrafish Fin, Developmental Cell, vol.20, issue.5, pp.713-737, 2011.
DOI : 10.1016/j.devcel.2011.04.014

S. Dallas, P. Veno, J. Rosser, C. Barragan-adjemian, D. Rowe et al., Time Lapse Imaging Techniques for Comparison of Mineralization Dynamics in Primary Murine Osteoblasts and the Late Osteoblast/Early Osteocyte-Like Cell Line MLO-A5, Cells Tissues Organs, vol.189, issue.1-4, pp.6-11, 2009.
DOI : 10.1159/000151745

E. Czekanska, M. Stoddart, J. Ralphs, R. Richards, and J. Hayes, A phenotypic comparison of osteoblast cell lines versus human primary osteoblasts for biomaterials testing, Journal of Biomedical Materials Research Part A, vol.258, issue.8, pp.2636-2679, 2014.
DOI : 10.1002/jbm.a.34937

K. Uchihashi, S. Aoki, A. Matsunobu, and S. Toda, Osteoblast migration into type I collagen gel and differentiation to osteocyte-like cells within a self-produced mineralized matrix: A novel system for analyzing differentiation from osteoblast to osteocyte, Bone, vol.52, issue.1, pp.102-112, 2013.
DOI : 10.1016/j.bone.2012.09.001

N. Ortega, D. Behonick, D. Stickens, and Z. Werb, How Proteases Regulate Bone Morphogenesis, Annals of the New York Academy of Sciences, vol.8, issue.1, pp.109-125, 2003.
DOI : 10.1111/j.1749-6632.2003.tb03214.x

K. Paiva and J. Granjeiro, Bone tissue remodeling and development: Focus on matrix metalloproteinase functions, Archives of Biochemistry and Biophysics, vol.561, pp.74-87, 2014.
DOI : 10.1016/j.abb.2014.07.034

Y. Chou, W. Huang, J. Dunn, T. Miller, and B. Wu, The effect of biomimetic apatite structure on osteoblast viability, proliferation, and gene expression, Biomaterials, vol.26, issue.3, pp.285-95, 2005.
DOI : 10.1016/j.biomaterials.2004.02.030

G. Alvarez, C. Helary, A. Mebert, X. Wang, T. Coradin et al., Antibiotic-loaded silica nanoparticle???collagen composite hydrogels with prolonged antimicrobial activity for wound infection prevention, Journal of Materials Chemistry B, vol.76, issue.29, pp.4660-70, 2014.
DOI : 10.1039/c4tb00327f

URL : https://hal.archives-ouvertes.fr/hal-01138991

L. Chen, J. Mccrate, J. Lee, and H. Li, The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells, Nanotechnology, vol.22, issue.10, p.105708, 2011.
DOI : 10.1088/0957-4484/22/10/105708

M. Stevens and J. George, Exploring and Engineering the Cell Surface Interface, Science, vol.310, issue.5751, pp.1135-1143, 2005.
DOI : 10.1126/science.1106587

T. Yuasa, Y. Miyamoto, K. Ishikawa, M. Takechi, Y. Momota et al., Effects of apatite cements on proliferation and differentiation of human osteoblasts in vitro, Biomaterials, vol.25, issue.7-8, pp.1159-66, 2004.
DOI : 10.1016/j.biomaterials.2003.08.003

S. Maxian, D. Stefano, T. Melican, M. Tiku, M. Zawadsky et al., Bone cell behavior on Matrigel???-coated Ca/P coatings of varying crystallinities, Journal of Biomedical Materials Research, vol.10, issue.2, pp.171-180, 1998.
DOI : 10.1002/(SICI)1097-4636(199805)40:2<171::AID-JBM1>3.0.CO;2-I

T. Sugimoto, M. Kanatani, J. Kano, H. Kaji, T. Tsukamoto et al., Effects of high calcium concentration on the functions and interactions of osteoblastic cells and monocytes and on the formation of osteoclast-like cells, Journal of Bone and Mineral Research, vol.155, issue.12, pp.1445-52, 1993.
DOI : 10.1002/jbmr.5650081206

S. Boonrungsiman, E. Gentleman, R. Carzaniga, N. Evans, D. Mccomb et al., The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation, Proceedings of the National Academy of Sciences, vol.109, issue.35, pp.14170-14175, 2012.
DOI : 10.1073/pnas.1208916109

M. Prideaux, N. Loveridge, A. Pitsillides, and C. Farquharson, Extracellular Matrix Mineralization Promotes E11/gp38 Glycoprotein Expression and Drives Osteocytic Differentiation, PLoS ONE, vol.26, issue.5, p.36786, 2012.
DOI : 10.1371/journal.pone.0036786.t001

K. Irie, S. Ejiri, Y. Sakakura, T. Shibui, and T. Yajima, Matrix Mineralization as a Trigger for Osteocyte Maturation, Journal of Histochemistry & Cytochemistry, vol.26, issue.6, pp.561-568, 2008.
DOI : 10.1038/ng1905