Skip to Main content Skip to Navigation
Journal articles

Incidence of urinary tract infections and antibiotic resistance in the outpatient setting: a cross-sectional study

Abstract : Purpose In 2012–2013, a cross-sectional survey was conducted in women visiting a general practitioner for urinary tract infection (UTI), to estimate the annual incidence of UTIs due to antibiotic-resistant Escherichia coli (E. coli). Methods A sampling design (stratification, stages and sampling weights) was taken into account in all analyses. Urine analyses were performed for each woman and centralised in one laboratory. Results Among 538 included women, urine culture confirmed UTI in 75.2 % of cases. E. coli represented 82.8 % of species. Among E. coli, resistance (I + R) was most common to amoxicillin [38 % (95 % confidence interval 31.1–44.5)] and to trimethoprim/sulfamethoxazole [18.1 % (12.0–24.1)]. Resistance to ciprofloxacin and cefotaxime was lower [1.9 % in both cases, (0.3–3.5)], as it was for nitrofurantoin [0.4 (0–1.0)] and fosfomycin (0). Extended-spectrum β-lactamase (ESBL) represented 1.6 % of E. coli (0.2–2.9). Annual incidence rate of confirmed UTI was estimated at 2400 per 100,000 women (1800–3000). Incidence rates of UTI due to fluoroquinolone-resistant and ESBL-producing E. coli were estimated at 102 per 100,000 women (75–129) and at 32 (24–41), respectively. Conclusions ESBL had been found in a community population, and even though the rate was low, it represents a warning and confirms that surveillance should continue.
Document type :
Journal articles
Complete list of metadata

Cited literature [22 references]  Display  Hide  Download

https://hal.sorbonne-universite.fr/hal-01324986
Contributor : Gestionnaire Hal-Upmc Connect in order to contact the contributor
Submitted on : Wednesday, June 1, 2016 - 4:45:47 PM
Last modification on : Thursday, December 10, 2020 - 12:36:02 PM
Long-term archiving on: : Friday, September 2, 2016 - 10:43:34 AM

File

Rossignol_2016_Incidence_of.pd...
Files produced by the author(s)

Identifiers

Citation

Louise Rossignol, Sophie Vaux, Sylvie Maugat, Alexandre Blake, Roxane Barlier, et al.. Incidence of urinary tract infections and antibiotic resistance in the outpatient setting: a cross-sectional study. Infection, Springer Verlag, 2016, 45 (1), pp.33-40. ⟨10.1007/s15010-016-0910-2⟩. ⟨hal-01324986⟩

Share

Metrics

Record views

295

Files downloads

1235