Targeting inflammation in cancer-related-fatigue: A rationale for mistletoe therapy as supportive care in colorectal cancer patients. Inflamm. Allergy Drug Targets Fermented mistletoe extract as a multimodal antitumoral agent in gliomas, pp.105-111, 2012. ,
Mistletoe in cancer?A systematic review on controlled clinical trials European Viscum album: A potent phytotherapeutic agent with multifarious phytochemicals, pharmacological properties and clinical evidence, Eur. J. Med. Res, vol.8, issue.6, pp.109-119, 2003. ,
Safety and efficacy of the long-term adjuvant treatment of primary intermediate-to high-risk malignant melanoma (UICC/AJCC stage II and III) with a standardized fermented European mistletoe (Viscum album L.) extract. Results from a multicenter, comparative, epidemiological cohort study in Germany and Switzerland, Arzneimittelforschung, vol.55, pp.38-49, 2005. ,
Efficacy and Safety of Mistletoe Preparations (Viscum album) for Patients with Cancer Diseases, Forschende Komplement??rmedizin / Research in Complementary Medicine, vol.16, issue.4, pp.217-226, 2009. ,
DOI : 10.1159/000226249
-glycosidase activity of the protein, FEBS Letters, vol.43, issue.2, pp.378-380, 1988. ,
DOI : 10.1016/0014-5793(88)80853-6
URL : https://hal.archives-ouvertes.fr/hal-00907229
Ribosome???Inactivating Proteins from Plants: Present Status and Future Prospects, Bio/Technology, vol.18, issue.4, pp.405-412, 1992. ,
DOI : 10.1038/nbt0492-405
Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses, Nature Immunology, vol.27, issue.4, pp.394-402, 2009. ,
DOI : 10.1038/ni.1707
Programming dendritic cells to induce TH2 and tolerogenic responses, Nature Immunology, vol.197, issue.8, pp.647-655, 2010. ,
DOI : 10.1038/ni.1894
Inflammatory dendritic cells???not basophils???are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen, The Journal of Experimental Medicine, vol.21, issue.10, pp.2097-2111, 2010. ,
DOI : 10.1016/S0092-8674(00)80240-8
Human Inflammatory Dendritic Cells Induce Th17 Cell Differentiation, Immunity, vol.38, issue.2, pp.336-348, 2013. ,
DOI : 10.1016/j.immuni.2012.10.018
Human B cells induce dendritic cell maturation and favour Th2 polarization by inducing OX-40 ligand, Nature Communications, vol.141, pp.2014-4092 ,
DOI : 10.1073/pnas.90.8.3730
Dendritic Cells: Arbiters of Immunity and Immunological Tolerance, Cold Spring Harbor Perspectives in Biology, vol.4, issue.8 ,
DOI : 10.1101/cshperspect.a007401
Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells, Blood, vol.120, issue.6, pp.1237-1245, 2012. ,
DOI : 10.1182/blood-2011-09-379776
FOXP3+ regulatory T cells and their functional regulation, Cellular and Molecular Immunology, vol.3, issue.5, pp.558-565 ,
DOI : 10.1073/pnas.1408780111
Repressing Immunity in Autoimmune Disease, New England Journal of Medicine, vol.374, issue.21, pp.2090-2092 ,
DOI : 10.1056/NEJMcibr1602864
Gabrilovich, D.I. Clinical significance of defective dendritic cell differentiation n cancer, Clin. Cancer Res, vol.6, pp.1755-1766, 2000. ,
Tumour escape from immune surveillance through dendritic cell inactivation, Seminars in Cancer Biology, vol.12, issue.1, pp.33-42, 2002. ,
DOI : 10.1006/scbi.2001.0400
Decreased antigen presentation by dendritic cells in patients with breast cancer, Clin. Cancer Res, vol.3, pp.483-490, 1997. ,
Relationship between the expression of vascular endothelial growth factor and the density of dendritic cells in gastric adenocarcinoma tissue, British Journal of Cancer, vol.78, issue.12, pp.1573-1577, 1998. ,
DOI : 10.1038/bjc.1998.725
Metabolic Influences That Regulate Dendritic Cell Function in Tumors, Frontiers in Immunology, vol.5, issue.5, p.24 ,
DOI : 10.3389/fimmu.2014.00024
The Role of Tumor/Dendritic Cell Interactions in the Regulation of Anti-Tumor Immunity: The Good, the Bad, and the Ugly, Frontiers in Immunology, vol.4, p.178, 2014. ,
DOI : 10.3389/fimmu.2013.00371
Induction of maturation and activation of human dendritic cells: A mechanism underlying the beneficial effect of Viscum albumas complimentary therapy in cancer, BMC Cancer, vol.210, issue.9, p.161, 2008. ,
DOI : 10.1016/j.imbio.2005.07.004
Human cancer cells exhibit in vitro individual receptiveness towards different mistletoe extracts, Pharmazie, vol.60, pp.448-454, 2005. ,
Differences in the in vitro effectiveness of preparations produced from mistletoes of various host trees, Arzneimittelforschung, vol.36, pp.433-436, 1986. ,
Mistletoe treatment for cancer review of controlled trials in humans, Phytomedicine, vol.1, issue.3, pp.255-260, 1994. ,
DOI : 10.1016/S0944-7113(11)80073-5
Comparison of the Effects of Fermented and Unfermented Mistletoe Preparations on Cultured Tumor Cells, Oncology, vol.43, issue.1, pp.35-41, 1986. ,
DOI : 10.1159/000226418
Mistletoe lectin is not the only cytotoxic component in fermented preparations of Viscum album from white fir (Abies pectinata), BMC Complementary and Alternative Medicine, vol.25, issue.6A, p.14, 2007. ,
DOI : 10.1042/bj20030488
Inflammatory Cytokines: Potential Biomarkers of Immunologic Dysfunction in Autism Spectrum Disorders, Mediators of Inflammation, vol.8, issue.3, 2015. ,
DOI : 10.1111/j.1471-4159.2009.06432.x
Functions of natural killer cells, Nature Immunology, vol.178, issue.5, pp.503-510, 2008. ,
DOI : 10.1073/pnas.050588297
URL : https://hal.archives-ouvertes.fr/hal-00294184
IFN? and lymphocytes prevent primary tumour development and shape tumour immunogenicity, Nature, vol.410, issue.6832, pp.1107-1111, 2001. ,
DOI : 10.1038/35074122
Roles of Idiotype-Specific T Cells in Myeloma Cell Growth and Survival: Th1 and CTL Cells Are Tumoricidal while Th2 Cells Promote Tumor Growth, Cancer Research, vol.68, issue.20, pp.8456-8464, 2008. ,
DOI : 10.1158/0008-5472.CAN-08-2213
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice, Proc. Natl. Acad ,
Cancer immunotherapy via dendritic cells, Nat. Rev. Cancer, vol.2012, issue.12, pp.265-277 ,
Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells, Blood, vol.122, issue.8, pp.1419-1427, 2013. ,
DOI : 10.1182/blood-2012-11-468264
Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation, Cellular and Molecular Immunology, vol.65, issue.5, pp.650-652, 2015. ,
DOI : 10.4049/jimmunol.1101029
Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E2-induced regulatory T cell expansion, Scientific Reports, vol.2 ,
DOI : 10.4049/jimmunol.0903174
URL : https://hal.archives-ouvertes.fr/hal-01304323
Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients, Blood, vol.108, issue.8, pp.2655-2661, 2006. ,
DOI : 10.1182/blood-2006-03-011353
Viscum album Exerts Anti-Inflammatory Effect by Selectively Inhibiting Cytokine-Induced Expression of Cyclooxygenase-2, PLoS ONE, vol.35, issue.10, p.26312, 2011. ,
DOI : 10.1371/journal.pone.0026312.t001
URL : https://hal.archives-ouvertes.fr/hal-00637405
Viscum album-Mediated COX-2 Inhibition Implicates Destabilization of COX-2 mRNA, PLOS ONE, vol.70, issue.2, 2015. ,
DOI : 10.1371/journal.pone.0114965.g004
URL : https://hal.archives-ouvertes.fr/hal-01344611
GAMMA-INTERFERON (IFN-??) AUGMENTS APOPTOTIC RESPONSE TO MISTLETOE LECTIN-II VIA UPREGULATION OF FAS/FAS L EXPRESSION AND CASPASE ACTIVATION IN HUMAN MYELOID U937 CELLS, Immunopharmacology and Immunotoxicology, vol.139, issue.5, pp.55-66, 2011. ,
DOI : 10.1081/IPH-100102567
Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis, Cancer Res, vol.59, pp.2083-2090, 1999. ,
Anti-mistletoe lectin antibodies are produced in patients during therapy with an aqueous mistletoe extract derived fromViscum album L. and neutralize lectin-induced cytotoxicity in vitro, Klinische Wochenschrift, vol.76, issue.227, pp.896-900, 1990. ,
DOI : 10.1007/BF01649034
Mechanisms Involved in Spontaneous and Viscum album Agglutinin-I-Induced Human Neutrophil Apoptosis: Viscum album Agglutinin-I Accelerates the Loss of Antiapoptotic Mcl-1 Expression and the Degradation of Cytoskeletal Paxillin and Vimentin Proteins Via Caspases, The Journal of Immunology, vol.168, issue.3, pp.1419-1427, 2002. ,
DOI : 10.4049/jimmunol.168.3.1419
The B-chain of mistletoe lectin I efficiently stimulates calcium signaling in human Jurkat T-cells, Immunology Letters, vol.78, issue.2, pp.57-66, 2001. ,
DOI : 10.1016/S0165-2478(01)00238-3
Biotinylated ligands for receptor localization: An alternative for immunohistochemistry, Zentralbl. Pathol, vol.137, pp.473-478, 1991. ,
Mistletoe lectin has a shiga toxin-like structure and should be combined with other Toll-like receptor ligands in cancer therapy, Cancer Immunology, Immunotherapy, vol.17, issue.1, pp.1283-1292, 2013. ,
DOI : 10.1007/s00262-013-1455-1
TLR4-mediated activation of mouse macrophages by Korean mistletoe lectin-C (KML-C), Biochemical and Biophysical Research Communications, vol.396, issue.3, pp.721-725, 2010. ,
DOI : 10.1016/j.bbrc.2010.04.169
Do aligned sequences share the same fold?, Journal of Molecular Biology, vol.273, issue.1, pp.355-368, 1997. ,
DOI : 10.1006/jmbi.1997.1287
Mistletoe therapy in oncology, Cochrane Database Syst. Rev, issue.2, p.3297, 2008. ,
Induction of apoptosis of endothelial cells by Viscum album: A role for anti-tumoral properties of mistletoe lectins, Mol. Med, vol.8, pp.600-606, 2002. ,
Differences in the apoptosis-inducing properties of Viscum album L. extracts, S9?S14. [CrossRef], 1997. ,
Serum levels of IL-12 and the production of IFN-gamma, IL-2 and IL-4 by peripheral blood mononuclear cells (PBMC) in cancer patients treated with Viscum album extract, Biomedicine & Pharmacotherapy, vol.54, issue.6, pp.305-310, 2000. ,
DOI : 10.1016/S0753-3322(00)80052-9
Influence of polysaccharides from Viscum album L. on human lymphocytes, monocytes and granulocytes in vitro, Anticancer Res, vol.19, pp.3907-3914, 1999. ,
Standardized mistletoe extract augments immune response and down-regulates local and metastatic tumor growth in murine models, Anticancer Res, vol.22, pp.4187-4190, 2002. ,
Interleukin-12 is associated with the in vivo anti-tumor effect of mistletoe extracts in B16 mouse melanoma, Cancer Letters, vol.243, issue.1, pp.32-37, 2006. ,
DOI : 10.1016/j.canlet.2005.11.016
Tumour cell derived effects on monocyte/macrophage polarization and function and modulatory potential of Viscum album lipophilic extract in vitro, BMC Complement. Altern. Med, pp.15-130, 2015. ,
A Natural Combination Extract of Viscum album L. Containing Both Triterpene Acids and Lectins Is Highly Effective against AML In Vivo, PLOS ONE, vol.125, issue.4, p.133892, 2015. ,
DOI : 10.1371/journal.pone.0133892.s001
GM-CSF along with IL-4 but not alone is indispensable for the differentiation of human dendritic cells from monocytes, Journal of Allergy and Clinical Immunology, vol.133, issue.5, pp.1500-1502, 2014. ,
DOI : 10.1016/j.jaci.2014.02.021