X. Shi, H. Zekki, and J. Zhang, The role of TLR2 in nerve injury-induced neuropathic pain is essentially mediated through macrophages in peripheral inflammatory response, Glia, vol.359, issue.2, pp.231-241, 2011.
DOI : 10.1179/096805102125001073

T. Lim, X. Shi, and H. Martin, Blood-nerve barrier dysfunction contributes to the generation of neuropathic pain and allows targeting of injured nerves for pain relief, Pain, vol.155, issue.5, pp.954-967, 2014.
DOI : 10.1016/j.pain.2014.01.026

J. Van-steenwinckel, C. Auvynet, and A. Sapienza, Stromal cell-derived CCL2 drives neuropathic pain states through myeloid cell infiltration in injured nerve, Brain, Behavior, and Immunity, vol.45, pp.198-210, 2015.
DOI : 10.1016/j.bbi.2014.10.016

N. Moreau, A. Mauborgne, and S. Bourgoin, Early alterations of Hedgehog signaling pathway in vascular endothelial cells after peripheral nerve injury elicit blood-nerve barrier disruption, nerve inflammation, and neuropathic pain development, PAIN, vol.157, issue.4, pp.827-839, 2016.
DOI : 10.1097/j.pain.0000000000000444

N. Moreau, W. Dieb, and A. Mauborgne, Hedgehog pathway-mediated vascular alterations following trigeminal nerve injury Epub ahead of print 16, J Dental Res, pp.10-1177, 2016.
DOI : 10.1177/0022034516679395

H. Zhang, Y. Li, and M. De-carvalho-barbosa, Dorsal Root Ganglion Infiltration by Macrophages Contributes to??Paclitaxel Chemotherapy-Induced Peripheral Neuropathy, The Journal of Pain, vol.17, issue.7, pp.775-786, 2016.
DOI : 10.1016/j.jpain.2016.02.011

T. Kanda, Biology of the blood???nerve barrier and its alteration in immune mediated neuropathies, Journal of Neurology, Neurosurgery & Psychiatry, vol.84, issue.2, pp.208-212, 2013.
DOI : 10.1136/jnnp-2012-302312

J. Alvarez, A. Dodelet-devillers, and H. Kebir, The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence, Science, vol.24, issue.2, pp.1727-1731, 2011.
DOI : 10.1016/j.jaut.2005.01.004

C. Chapouly, Q. Yao, and S. Vandierdonck, Impaired Hedgehog signalling-induced endothelial dysfunction is sufficient to induce neuropathy: implication in diabetes, Cardiovascular Research, vol.109, issue.2, pp.217-227, 2016.
DOI : 10.1093/cvr/cvv263

C. Franco, S. Liebner, and G. H. , Vascular morphogenesis: a Wnt for every vessel?, Current Opinion in Genetics & Development, vol.19, issue.5, pp.476-483, 2009.
DOI : 10.1016/j.gde.2009.09.004

E. Dejena, The Role of Wnt Signaling in Physiological and Pathological Angiogenesis, Circulation Research, vol.107, issue.8, pp.943-952, 2010.
DOI : 10.1161/CIRCRESAHA.110.223750

M. Reis and S. Liebner, Wnt signaling in the vasculature, Experimental Cell Research, vol.319, issue.9, pp.1317-1323, 2013.
DOI : 10.1016/j.yexcr.2012.12.023

T. Ferreira, C. Peghaire, and N. Franzl, Frizzled7 controls vascular permeability through the Wnt-canonical pathway and cross-talk with endothelial cell junction complexes, Cardiovascular Research, vol.103, issue.2, pp.291-303, 2014.
DOI : 10.1093/cvr/cvu133

H. Clevers and R. Nusse, Wnt/??-Catenin Signaling and Disease, Cell, vol.149, issue.6, pp.1192-1205, 2012.
DOI : 10.1016/j.cell.2012.05.012

T. Itokazu, Y. Hayano, and R. Takahashi, Involvement of Wnt/??-catenin signaling in the development of neuropathic pain, Neuroscience Research, vol.79, pp.34-40, 2014.
DOI : 10.1016/j.neures.2013.12.002

M. Simonetti, N. Agarwal, and S. Sto¨ssersto¨sser, Wnt-Fzd Signaling Sensitizes Peripheral Sensory Neurons via Distinct Noncanonical Pathways, Neuron, vol.83, issue.1, pp.104-121, 2014.
DOI : 10.1016/j.neuron.2014.05.037

URL : http://doi.org/10.1016/j.neuron.2014.05.037

Z. Xu, Y. Chen, and J. Yu, TCF4 Mediates the Maintenance of Neuropathic Pain Through Wnt/??-Catenin Signaling Following Peripheral Nerve Injury in Rats, Journal of Molecular Neuroscience, vol.123, issue.2, pp.397-408, 2015.
DOI : 10.1016/0304-3959(83)90201-4

J. Wang, S. Thang, and L. Li, Involvement of Wnt5a within the cerebrospinal fluid-contacting nucleus in nerve injury-induced neuropathic pain, International Journal of Neuroscience, vol.107, issue.2, pp.147-153, 2015.
DOI : 10.1073/pnas.1010011107

M. Zimmermann, Ethical guidelines for investigations of experimental pain in conscious animals, Pain, vol.16, issue.2, pp.109-110, 1983.
DOI : 10.1016/0304-3959(83)90201-4

W. Dieb and A. Hafidi, Astrocytes are Involved in Trigeminal Dynamic Mechanical Allodynia, Journal of Dental Research, vol.22, issue.356, pp.808-813, 2013.
DOI : 10.1016/j.bbrc.2005.12.139

L. Yen, V. Wei, and E. Kuo, Distinct Patterns of Cerebral Extravasation by Evans Blue and Sodium Fluorescein in Rats, PLoS ONE, vol.6, issue.7, p.68595, 2013.
DOI : 10.1371/journal.pone.0068595.g006

K. Livak and T. Schmittgen, Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2???????CT Method, Methods, vol.25, issue.4, pp.402-408, 2001.
DOI : 10.1006/meth.2001.1262

J. Gavard and J. Gutkind, VE-cadherin and claudin-5: it takes two to tango, Nature Cell Biology, vol.115, issue.8, pp.883-885, 2008.
DOI : 10.1038/84675

URL : https://hal.archives-ouvertes.fr/hal-00340308

B. Vos, A. Strassman, and R. Maciewicz, Behavioral evidence of trigeminal neuropathic pain following chronic constriction injury to the rat's infraorbital nerve

A. Taddei, C. Giampietro, and A. Conti, Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5, Nature Cell Biology, vol.72, issue.8, pp.923-934, 2008.
DOI : 10.1016/S1534-5807(02)00401-X

J. Gavard, Breaking the VE-cadherin bonds, FEBS Letters, vol.108, issue.1, pp.1-6, 2009.
DOI : 10.1002/jcp.21354

URL : https://hal.archives-ouvertes.fr/hal-00345388

Y. Shi, S. Yuan, and B. Li, Regulation of Wnt Signaling by Nociceptive Input in Animal Models, Molecular Pain, vol.20, p.47, 2012.
DOI : 10.1016/S0304-3959(98)00197-3

Y. Zhang, Z. Huang, and S. Liu, WNT signaling underlies the pathogenesis of neuropathic pain in rodents, Journal of Clinical Investigation, vol.123, issue.5, pp.2268-2286, 2013.
DOI : 10.1172/JCI65364DS1

N. Kiguchi, Y. Kobayashi, and Y. Kadowaki, Vascular endothelial growth factor signaling in injured nerves underlies peripheral sensitization in neuropathic pain, Journal of Neurochemistry, vol.120, issue.1, pp.169-178, 2014.
DOI : 10.1182/blood-2012-01-403386

J. Mazumdar, O. Brien, W. Johnson, and R. , O2 regulates stem cells through Wnt/??-catenin signalling, Nature Cell Biology, vol.136, issue.10, pp.1007-1013, 2010.
DOI : 10.1172/JCI17669

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144143

X. Song, Y. Zhou, and Y. Huang, Wogonin influences vascular permeability via Wnt/??-catenin pathway, Molecular Carcinogenesis, vol.222, issue.7, pp.501-512, 2015.
DOI : 10.1016/j.toxlet.2013.07.013

T. Lim, X. Shi, and J. Johnson, Peripheral Nerve Injury Induces Persistent Vascular Dysfunction and Endoneurial Hypoxia, Contributing to the Genesis of Neuropathic Pain, Journal of Neuroscience, vol.35, issue.8, pp.3346-3359, 2015.
DOI : 10.1523/JNEUROSCI.4040-14.2015

E. Dejana and F. Orsenigo, Endothelial adherens junctions at a glance, Journal of Cell Science, vol.126, issue.12, pp.2545-2549, 2013.
DOI : 10.1242/jcs.124529

URL : http://jcs.biologists.org/content/joces/126/12/2545.full.pdf

R. Das and K. Storey, Apical Abscission Alters Cell Polarity and Dismantles the Primary Cilium During Neurogenesis, Science, vol.262, issue.16, pp.200-204, 2014.
DOI : 10.1074/jbc.M405319200

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066580

Y. Miyamoto, F. Sakane, and K. Hashimoto, N-cadherin-based adherens junction regulates the maintenance, proliferation, and differentiation of neural progenitor cells during development, Cell Adhesion & Migration, vol.5, issue.8, pp.183-192, 2015.
DOI : 10.1038/nn.2243

R. Myers, T. Yamamoto, and T. Yaksh, The Role of Focal Nerve Ischemia and Wallerian Degeneration in Peripheral Nerve Injury Producing Hyperesthesia, Anesthesiology, vol.78, issue.2, pp.308-316, 1993.
DOI : 10.1097/00000542-199302000-00015

J. Gavard and J. Gutkind, VEGF controls endothelial-cell permeability by promoting the ??-arrestin-dependent endocytosis of VE-cadherin, Nature Cell Biology, vol.280, issue.11, pp.1223-1234, 2006.
DOI : 10.1091/mbc.10.1.9

F. Orsenigo, Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo, Nature Communications, vol.86, p.1208, 2012.
DOI : 10.1529/biophysj.103.038422

B. Coon, N. Baeyens, and J. Han, Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex, The Journal of Cell Biology, vol.96, issue.7, pp.975-986, 2015.
DOI : 10.1002/path.969

A. Sapienza, R. Goazigo, A. Rostè-ne, and W. , Chimiokines et attractivit?? des cellules my??lo??des dans les douleurs neuropathiques p??riph??riques, Biologie Aujourd'hui, vol.208, issue.1, pp.31-44, 2014.
DOI : 10.1051/jbio/20140011

H. Hirakawa, S. Okajima, and T. Nagaoka, Loss and recovery of the blood???nerve barrier in the rat sciatic nerve after crush injury are associated with expression of intercellular junctional proteins, Experimental Cell Research, vol.284, issue.2, pp.196-210, 2003.
DOI : 10.1016/S0014-4827(02)00035-6

S. Peltonen, M. Alanne, and J. Peltonen, Barriers of the peripheral nerve, Tissue Barriers, vol.12, issue.3, pp.24956-24957, 2013.
DOI : 10.1126/science.285.5424.103

G. Bennett and Y. Xie, A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man, Pain, vol.33, issue.1, pp.87-107, 1988.
DOI : 10.1016/0304-3959(88)90209-6

T. Walsh, R. Murphy, and P. Fitzpatrick, Stabilization of brain microvascular endothelial barrier function by shear stress involves VE-cadherin signaling leading to modulation of pTyr-occludin levels, Journal of Cellular Physiology, vol.285, issue.11, pp.3053-3063, 2011.
DOI : 10.1152/ajplung.00423.2002

H. Nukada, H. Powell, and R. Myers, Spatial Distribution of Nerve Injury after Occlusion of Individual Major Vessels in Rat Sciatic Nerves, Journal of Neuropathology and Experimental Neurology, vol.52, issue.5, pp.452-459, 1993.
DOI : 10.1097/00005072-199309000-00003

R. Myers and V. Shubayev, The ology of neuropathy: an integrative review of the role of neuroinflammation and TNF-?? axonal transport in neuropathic pain, Journal of the Peripheral Nervous System, vol.116, issue.4, pp.277-286, 2011.
DOI : 10.1042/CS20080196

W. Xie, J. Strong, and J. Meij, Neuropathic pain: Early spontaneous afferent activity is the trigger, Pain, vol.116, issue.3, pp.243-256, 2005.
DOI : 10.1016/j.pain.2005.04.017

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1343516

A. Basbaum, D. Bautista, and G. Scherrer, Cellular and Molecular Mechanisms of Pain, Cell, vol.139, issue.2, pp.267-284, 2009.
DOI : 10.1016/j.cell.2009.09.028