W. Gilbert, Origin of life: The RNA world, Nature, vol.319, pp.618-618, 1986.

A. Lazcano and S. L. Miller, The Origin and Early Evolution of Life: Prebiotic Chemistry, the Pre-RNA World, and Time, Cell, vol.85, pp.793-798, 1996.

S. A. Benner, H. Kim, and Z. Yang, Setting the Stage: The History, Chemistry, and Geobiology behind RNA, Cold Spring Harb. Perspect. Biol, 2012.

J. D. Sutherland, The Origin of Life-Out of the Blue, Angew. Chem. Int. Ed, vol.55, pp.104-121, 2016.

J. Oró, Synthesis of adenine from ammonium cyanide, Biochem. Biophys. Res. Commun, vol.2, pp.407-412, 1960.

R. A. Sanchez, J. P. Ferris, and L. E. Orgel, Studies in prebiotic synthesis, J. Mol. Biol, vol.38, pp.121-128, 1968.

M. P. Robertson and S. L. Miller, An efficient prebiotic synthesis of cytosine and uracil, Nature, vol.375, pp.772-774, 1995.

J. S. Hudson, J. F. Eberle, R. H. Vachhani, L. C. Rogers, J. H. Wade et al., A Unified Mechanism for Abiotic Adenine and Purine Synthesis in Formamide, Angew. Chem. Int. Ed, vol.51, pp.5134-5137, 2012.

G. Torrie and J. Valleau, Nonphysical sampling distributions in Monte Carlo free-energy estimation: Umbrella sampling, J. Comput. Phys, vol.23, pp.187-199, 1977.

F. Pietrucci, Strategies for the exploration of free energy landscapes: unity in diversity and challenges ahead, Rev. Phys, vol.2, pp.32-45, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01534581

F. Pietrucci and A. M. Saitta, Formamide reaction network in gas phase and solution via a unified theoretical approach: Toward a reconciliation of different prebiotic scenarios

, Proc. Natl. Acad. Sci. U.S.A, vol.112, pp.15030-15035, 2015.

F. Pietrucci, J. C. Aponte, R. D. Starr, A. Pérez-villa, J. E. Elsila et al., Hydrothermal Decomposition of Amino Acids and Origins of Prebiotic Meteoritic Organic Compounds, ACS Earth Space Chem, 2018.
URL : https://hal.archives-ouvertes.fr/hal-01922098

M. P. Kroonblawd, F. Pietrucci, A. M. Saitta, and N. Goldman, Generating Converged Accurate Free Energy Surfaces for Chemical Reactions with a Force-Matched Semiempirical Model, J. Chem. Theory Comput, vol.14, pp.2207-2218, 2018.

G. Cassone, J. Sponer, J. E. Sponer, F. Pietrucci, A. M. Saitta et al., ELF: The electron localization function, Angew. Chem. Int. Ed, vol.36, issue.48, pp.1808-1832, 1997.

A. P. Camargo, H. Baumgartel, and C. Donner, Coadsorption of the DNA bases thymine and adenine at the Au(111) electrode, Phys. Chem. Chem. Phys, vol.5, pp.1657-1664, 2003.

S. Ganguly and K. K. Kundu, Protonation/deprotonation energetics of uracil, thymine, and cytosine in water from e.m.f./spectrophotometric measurements, Can. J. Chem, vol.72, pp.1120-1126, 1994.

C. A. Cole, Z. Wang, T. P. Snow, and V. M. Bierbaum, Anionic derivatives of uracil: fragmentation and reactivity, Phys. Chem. Chem. Phys, vol.16, pp.17835-17844, 2014.

D. Silva, L. Maurel, M. Deamer, and D. , Salt-Promoted Synthesis of RNA-like Molecules in Simulated Hydrothermal Conditions, J. Mol. Evol, vol.80, pp.86-97, 2015.

S. Becker,

C. Schneider,

H. Okamura,

A. Crisp,

T. Amatov,

M. Dejmek,

T. Barone, V. Casarin, M. Forrer, D. Pavone, M. Sambi et al., Role and effective treatment of dispersive forces in materials: Polyethylene and graphite crystals as test cases, J. Comput. Chem, vol.30, issue.56, pp.934-939, 2009.

N. Troullier and J. L. Martins, Efficient pseudopotentials for plane-wave calculations, Phys. Rev. B, vol.43, 1991.

, CPMD Copyright IBM Corp. and by Max Planck Institute Stuttgart, 2000.

S. Nosé, A unified formulation of the constant temperature molecular dynamics methods, J. Chem. Phys, vol.81, pp.511-519, 1984.

W. G. Hoover, Canonical dynamics: Equilibrium phase-space distributions, Phys. Rev. A, vol.31, pp.1695-1697, 1985.

D. Branduardi, F. L. Gervasio, and M. Parrinello, From A to B in free energy space, J. Chem. Phys, p.54103, 2007.

P. G. Bolhuis, D. Chandler, C. Dellago, P. L. Geissler, . Transition et al., Throwing Ropes Over Rough Mountain Passes, in the Dark, Annu. Rev. Phys. Chem, vol.53, pp.291-318, 2002.