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Journal Articles Natural Product Research Year : 2018

An isoindole alkaloid from Portulaca oleracea L.

Abstract

A novel isoindole alkaloid named oleraisoindole (1), together with six known compounds, 7′-ethoxy-trans-feruloyltyramine (2), N-trans-feruloyltyramine (3), N-trans-feruloyl-3-methoxytyramine (4), N-trans-p-coumaroyltyramine (5) aurantiamide (6) and ferulic acid methyl ester (7) were isolated from Portulaca oleracea L. Compounds 2 and 7 were isolated for the first time from this plant. Compound 1 was identified using spectroscopic methods including HR-ESI-TOF-MS, 1D-NMR, 2D-NMR. It was tested in a nitric oxide (NO) inhibition assay and was shown to inhibit NO production in RAW 264.7 cells induced by LPS.
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Dates and versions

hal-02017383 , version 1 (13-02-2019)

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Mingyue Jiang, Wenjie Zhang, Xu Yang, Fen Xiu, Haoran Xu, et al.. An isoindole alkaloid from Portulaca oleracea L.. Natural Product Research, 2018, 32 (20), pp.2431-2436. ⟨10.1080/14786419.2017.1419226⟩. ⟨hal-02017383⟩
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