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Atteinte coronarienne et syndrome néphrotique au cours du lupus systémique : à propos d’une observation

Abstract : Introduction : Heart failure during systemic lupus erythematosus has various causes. Case report : A 29-year-old female presented with a systemic lupus flare and a nephrotic syndrome, followed by cardiogenic shock requiring extra-corporeal membranous oxygenation. Ventricular dysfunction was related to massive myocardial infarction due to an anterior interventricular artery thrombosis and an underlying atheroma. The young age and the absence of chest pain were not suggestive of coronary artery disease initially. Coronary thrombosis was probably favored by the nephrotic syndrome, in which the arterial thrombotic risk is increased. Conclusion : Coronary artery disease should be systematically evoked in the presence of ventricular dysfunction in patients with systemic lupus, including when they are young and in the absence of chest pain. Nephrotic syndrome should be identified as a risk factor for arterial thrombosis.
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Q. Moyon, M. Schmidt, A. Hertig, P. Fouret, D. Vauthier-Brouzes, et al.. Atteinte coronarienne et syndrome néphrotique au cours du lupus systémique : à propos d’une observation. La Revue De Médecine Interne, Elsevier, 2019, 40 (6), pp.395-399. ⟨10.1016/j.revmed.2019.03.001⟩. ⟨hal-02404368⟩

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