Self‐Assembled Collagen Microparticles by Aerosol as a Versatile Platform for Injectable Anisotropic Materials
Abstract
innovative spray-processing approach enables fast and cheap production of anisotropic microparticles containing >90 wt% type I collagen. Their injection in a biological medium results in the formation of fibrils retaining innate molecular characteristics while forming ordered, organized structures at higher length scales. The encapsulation of temperature-sensitive stem-cell products demonstrates the versatility of the approach for tissue regeneration applications. 20 µm Encapsulation Injection Type I collagen molecules in soluƟon Gingival MSCs SecreƟon factors 20 µm SPRAY-DRYING
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