J. Park, Y. Lee, and S. Lee, The Comparison of Mydriatic Effect between Two Drugs of Different Mechanism, Korean J. Ophthalmol, vol.23, p.40, 2009.

A. Behndig and J. Korobelnik, Mydriatic insert and intracameral injections compared with mydriatic eyedrops in cataract surgery: Controlled studies, J. Cataract Refract. Surg, vol.41, pp.1503-1519, 2015.

P. H. Heller, F. Perry, D. L. Jewett, and J. D. Levine, Autonomic components of the human pupillary light reflex, Investig. Ophthalmol. Vis. Sci, vol.31, pp.156-162, 1990.

J. Beatty, B. Lucero-wagner, G. Berntson, J. T. Cacioppo, and L. G. Tassinary, The pupillary system, Handbook of Psychophysiology, pp.142-162, 2000.

A. Urtti, Challenges and obstacles of ocular pharmacokinetics and drug delivery, Adv. Drug Deliv. Rev, vol.58, pp.1131-1135, 2006.

L. Salminen, Review: Systemic Absorption of Topically Applied Ocular Drugs in Humans, J. Ocul. Pharmacol. Ther, vol.6, pp.243-249, 1990.

A. Urtti and L. Salminen, Minimizing systemic absorption of topically administered ophthalmic drugs, Surv. Ophthalmol, vol.37, pp.435-456, 1993.

R. Malhotra, G. Banerjee, W. Brampton, and N. C. Price, Comparison of the cardiovascular effects of 2.5% phenylephrine and 10% phenylephrine during ophthalmic surgery, vol.12, pp.973-975, 1998.

C. Cagini, A. Caricato, G. Tosi, A. Pascale, C. Cesari et al., Evaluation of the Efficacy and Safety of the Ophthalmic Insert Mydriasert in Patients Undergoing Retinal Angiography, Eur. J. Ophthalmol, vol.24, pp.728-734, 2014.

C. Torrón, P. Calvo, O. Ruiz-moreno, J. Leciñena, and A. Pérez-iñigo, Use of a New Ocular Insert versus Conventional Mydriasis in Cataract Surgery, BioMed Res. Int, 2013.

M. Labetoulle, O. Findl, F. Malecaze, J. Alió, B. Cochener et al., Evaluation of the efficacy and safety of a standardised intracameral combination of mydriatics and anaesthetics for cataract surgery, Br. J. Ophthalmol, vol.100, pp.976-985, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01404089

C. B. Schulz, S. V. Goverdhan, and R. C. Humphry, An evaluation of intracameral mydriasis for routine cataract surgery, Br. J. Ophthalmol, vol.102, pp.784-789, 2018.

P. Destruel, N. Zeng, J. Seguin, S. Douat, F. Rosa et al., Novel in situ gelling ophthalmic drug delivery system based on gellan gum and hydroxyethylcellulose: Innovative rheological characterization, in vitro and in vivo evidence of a sustained precorneal retention time, Int. J

H. Almeida, M. H. Amaral, P. Lobão, and J. M. Lobo, In situ gelling systems: A strategy to improve the bioavailability of ophthalmic pharmaceutical formulations, Drug Discov. Today, vol.19, pp.400-412, 2014.

T. S. Tinu, T. Litha, and K. B. Anil, Polymers Used in Ophthalmic in Situ Gelling System, Int. J. Pharm. Sci. Rev. Res, vol.20, pp.176-183, 2013.

I. D. Rupenthal, C. R. Green, and R. G. Alany, Comparison of ion-activated in situ gelling systems for ocular drug delivery. Part 1: Physicochemical characterisation and in vitro release, Int. J. Pharm, vol.411, pp.69-77, 2011.

Q. Bao, J. Shen, R. Jog, C. Zhang, B. Newman et al., In vitro release testing method development for ophthalmic ointments, Int. J. Pharm, vol.526, pp.145-156, 2017.

N. Zeng, G. Dumortier, M. Maury, N. Mignet, and V. Boudy, Influence of additives on a thermosensitive hydrogel for buccal delivery of salbutamol: Relation between micellization, gelation, mechanic and release properties, Int. J. Pharm, vol.467, pp.70-83, 2014.

M. Jug, A. Hafner, J. Lovri?, M. L. Kregar, I. Pepi? et al., An overview of in vitro dissolution/release methods for novel mucosal drug delivery systems, J. Pharm. Biomed. Anal, vol.147, pp.350-366, 2018.

, USP 42-NF, vol.37, 2019.

U. S. Pharmacopeia, United States Pharmacopeial Convention, 2019.

, Semisolid Drug Products-performance Tests; United States Pharmacopeia and National Formulary, USP 42-NF, vol.37, 1724.

P. Costa and J. M. Lobo, Modeling and comparison of dissolution profiles, Eur. J. Pharm. Sci, vol.13, pp.123-133, 2001.

J. Siepmann and N. A. Peppas, Higuchi equation: Derivation, applications, use and misuse, Int. J. Pharm, vol.418, pp.6-12, 2011.

R. W. Korsmeyer, R. Gurny, E. Doelker, P. Buri, and N. A. Peppas, Mechanisms of solute release from porous hydrophilic polymers, Int. J. Pharm, vol.15, pp.25-35, 1983.

N. A. Peppas and J. J. Sahlin, A simple equation for the description of solute release. III. Coupling of diffusion and relaxation, Int. J. Pharm, vol.57, pp.169-172, 1989.

V. Papadopoulou, K. Kosmidis, M. Vlachou, and P. Macheras, On the use of the Weibull function for the discernment of drug release mechanisms, Int. J. Pharm, vol.309, pp.44-50, 2006.

K. Kosmidis, P. Argyrakis, and P. Macheras, A Reappraisal of Drug Release Laws Using Monte Carlo Simulations: The Prevalence of the Weibull Function, Pharm. Res, vol.20, pp.988-995, 2003.

H. B. Hopfenberg, Controlled Release from Erodible Slabs, Cylinders, and Spheres, Controlled Release Polymeric Formulations

D. R. Paul and F. W. Harris, , pp.26-32, 1976.

P. Costa and J. M. Lobo, Evaluation of Mathematical Models Describing Drug Release from Estradiol Transdermal Systems, Drug Dev. Ind. Pharm, vol.29, pp.89-97, 2003.

Y. Zhang, M. Huo, J. Zhou, A. Zou, W. Li et al., DDSolver: An add-in program for modeling and comparison of drug dissolution profiles, AAPS J, vol.12, pp.263-271, 2010.

N. Zeng, J. Seguin, P. Destruel, G. Dumortier, M. Maury et al., Cyanine derivative as a suitable marker for thermosensitive in situ gelling delivery systems: In vitro and in vivo validation of a sustained buccal drug delivery, Int. J. Pharm, vol.534, pp.128-135, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02123148

N. A. Peppas and B. Narasimhan, Mathematical models in drug delivery: How modeling has shaped the way we design new drug delivery systems, J. Control. Release, vol.190, pp.75-81, 2014.

I. D. Rupenthal, C. R. Green, and R. G. Alany, Comparison of ion-activated in situ gelling systems for ocular drug delivery. Part 2: Precorneal retention and in vivo pharmacodynamic study, Int. J. Pharm, vol.411, pp.78-85, 2011.

M. D. Abramoff, J. Paulo, and J. Sunada, Image processing with, ImageJ. Biophotonics Int, vol.11, pp.36-42, 2004.

P. Destruel, N. Zeng, M. Maury, N. Mignet, and V. Boudy, In vitro and in vivo evaluation of in situ gelling systems for sustained topical ophthalmic delivery: State of the art and beyond, Drug Discov. Today, vol.22, pp.638-651, 2017.

Y. Fu and W. J. Kao, Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems, Expert Opin. Drug Deliv, vol.7, pp.429-444, 2010.

V. Shah, Y. Tsong, P. Sathe, and J. Liu, In vitro dissolution profile comparison -Statistics and analysis of the similarity factor, f2, Pharm. Res, vol.15, pp.889-896, 1998.

J. Siepmann and N. A. Peppas, Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC), Adv. Drug Deliv. Rev, vol.19, pp.163-174, 2001.

Q. Bao, R. Jog, J. Shen, B. Newman, Y. Wang et al., Physicochemical attributes and dissolution testing of ophthalmic ointments, Int. J. Pharm, vol.523, pp.310-319, 2017.

A. Fernández-ferreiro, M. G. Barcia, M. Gil-martínez, A. Vieites-prado, I. Lema et al., In vitro and in vivo ocular safety and eye surface permanence determination by direct and Magnetic Resonance Imaging of ion-sensitive hydrogels based on gellan gum and kappa-carrageenan, Eur. J. Pharm. Biopharm, vol.94, pp.342-351, 2015.

E. R. Morris, K. Nishinari, and M. Rinaudo, Gelation of gellan-A review. Food Hydrocoll, vol.28, pp.373-411, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00720321

P. W. Heng, L. W. Chan, M. G. Easterbrook, and X. Li, Investigation of the influence of mean HPMC particle size and number of polymer particles on the release of aspirin from swellable hydrophilic matrix tablets, J. Control. Release, vol.76, pp.39-49, 2001.

R. Ek, T. Gren, U. Henriksson, H. Nyqvist, C. Nyström et al., Prediction of drug release by characterisation of the tortuosity in porous cellulose beads using a spin echo NMR technique, Int. J. Pharm, vol.124, pp.9-18, 1995.

T. Caruba, C. Couffon-partant, J. Oliary, R. Tadayoni, N. Limelette et al., Mydriase préopératoire obtenue par insert ophtalmique versus collyres, J. Fr. Ophtalmol, vol.29, pp.789-795, 2006.

B. Añíbarro, P. Barranco, and J. A. Ojeda, Allergic contact blepharoconjunctivitis caused by phenylephrine eyedrops, Contact Dermat, vol.25, pp.323-324, 1991.