C. Igg, Electron microscopy showing (C) subepithelial and (D) tubular basement membrane deposits. E-Sema3B staining along the glomerular basement membrane. (F) Higher power showing that the tubular basement membranes are negative for Sema3B (60x)

, Supplementary Material Methods: Details of laser microdissection and mass spectrometry Supplemental figure 1: An example of MS/MS spectra match to a sequence from Sema3B

L. H. Beck and D. J. Salant, Membranous nephropathy: from models to man, The Journal of Clinical Investigation, vol.124, pp.2307-2314, 2014.

P. Ronco and H. Debiec, Pathophysiological advances in membranous nephropathy: time for a shift in patient's care, The Lancet, vol.385, pp.1983-1992, 2015.

W. G. Couser, Primary Membranous Nephropathy, Clinical Journal of the American Society of Nephrology, vol.12, pp.983-997, 2017.

N. M. Tomas, L. H. Beck, and C. Meyer-schwesinger, Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathy, New England Journal of Medicine, vol.371, pp.2277-2287, 2014.

L. H. Beck, R. Bonegio, and L. Gr, M-Type Phospholipase A2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy, New England Journal of Medicine, vol.361, pp.11-21, 2009.
URL : https://hal.archives-ouvertes.fr/hal-00417718

S. Sethi, H. Debiec, and B. Madden, Neural epidermal growth factor-like 1 protein (NELL-1) associated membranous nephropathy, Kidney International, vol.97, pp.163-174, 2020.
URL : https://hal.archives-ouvertes.fr/hal-02433666

S. Sethi, B. J. Madden, and H. Debiec, Exostosin 1/Exostosin 2-Associated Membranous Nephropathy, Journal of the American Society of Nephrology, vol.30, pp.1123-1136, 2019.
URL : https://hal.archives-ouvertes.fr/inserm-02193818

F. Guan, G. Villegas, and J. Teichman, Autocrine class 3 semaphorin system regulates slit diaphragm proteins and podocyte survival, Kidney International, vol.69, pp.1564-1569, 2006.

L. T. Alto and J. R. Terman, Semaphorins and their Signaling Mechanisms

, Semaphorin Signaling: Methods and Protocols, pp.1-25, 2017.

U. Yazdani and J. R. Terman, The semaphorins, Genome Biology, vol.7, p.211, 2006.

H. Takamatsu and A. Kumanogoh, Diverse roles for semaphorin?plexin signaling in the immune system, Trends in Immunology, vol.33, pp.127-135, 2012.

G. Neufeld, Y. Mumblat, and T. Smolkin, The semaphorins and their receptors as modulators of tumor progression, Drug Resistance Updates, vol.29, pp.1-12, 2016.

R. Tapia, F. Guan, and I. Gershin, Semaphorin3a disrupts podocyte foot processes causing acute proteinuria, Kidney International, vol.73, pp.733-740, 2008.

M. Prunotto, M. L. Carnevali, and G. Candiano, Autoimmunity in Membranous Nephropathy Targets Aldose Reductase and SOD2, Journal of the American Society of Nephrology, vol.21, p.507, 2010.

A. Nesvizhskii, A. Keller, and E. Kolker, A Statistical Model for Identifying Proteins by Tandem Mass Spectrometry, Anal Chem, vol.75, pp.4646-4658, 2003.