Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome, Cell, vol.67, issue.2, pp.437-447, 1991. ,
The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells, Dev. Biol, vol.249, issue.1, pp.16-29, 2002. ,
WT-1 is required for early kidney development, Cell, vol.74, issue.4, pp.679-691, 1993. ,
A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome, Proc. Natl. Acad. Sci. USA, vol.96, issue.6, pp.2931-2936, 1999. ,
MafB is essential for renal development and F4/80 expression in macrophages, Mol. Cell Biol, vol.26, issue.15, pp.5715-5727, 2006. ,
Overexpression of Mafb in podocytes protects against diabetic nephropathy, J. Am. Soc. Nephrol, vol.25, issue.11, pp.2546-2557, 2014. ,
A mutation in transcription factor MAFB causes focal segmental glomerulosclerosis with duane retraction syndrome, Kidney Int, vol.94, issue.2, pp.396-407, 2018. ,
Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidney, Mech. Dev, vol.71, issue.1-2, pp.37-48, 1998. ,
, Scientific RepoRtS |, vol.10, p.11516, 2020.
epicardin: A novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads, Dev. Dyn, vol.213, issue.1, pp.105-113, 1998. ,
The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis, Development, vol.126, issue.24, pp.5771-5783, 1999. ,
Loss of the podocyte-expressed transcription factor Tcf21/Pod1 results in podocyte differentiation defects and FSGS, J. Am. Soc. Nephrol, vol.25, issue.11, pp.2459-2470, 2014. ,
Pod1 is required in stromal cells for glomerulogenesis, Dev. Dyn, vol.226, issue.3, pp.512-522, 2003. ,
Differentiating primary, genetic, and secondary FSGS in adults: a clinicopathologic approach, J. Am. Soc. Nephrol, vol.29, issue.3, pp.759-774, 2018. ,
Altered gene expression related to glomerulogenesis and podocyte structure in early diabetic nephropathy of db/ db mice and its restoration by pioglitazone, Diabetes, vol.55, issue.10, pp.2747-2756, 2006. ,
Sumoylation of TCF21 downregulates the transcriptional activity of estrogen receptor-alpha, Oncotarget, vol.7, issue.18, pp.26220-26234, 2016. ,
Urinary exosomal transcription factors, a new class of biomarkers for renal disease, Kidney Int, vol.74, issue.5, pp.613-621, 2008. ,
Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome, Kidney Int, vol.78, issue.8, pp.810-816, 2010. ,
Immunohistochemical study of the membrane attack complex of complement and S-protein in idiopathic and secondary membranous nephropathy, Am. J. Pathol, vol.135, issue.3, pp.469-476, 1989. ,
Dexamethasone prevents podocyte apoptosis induced by puromycin aminonucleoside: role of p53 and Bcl-2-related family proteins, J. Am. Soc. Nephrol, vol.16, issue.9, pp.2615-2625, 2005. ,
Apoptosis in podocytes induced by TGF-beta and Smad7, J. Clin. Invest, vol.108, issue.6, pp.807-816, 2001. ,
Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway, J. Am. Soc. Nephrol, vol.16, issue.7, pp.1936-1947, 2005. ,
Cyclin-dependent kinase 2 protects podocytes from apoptosis, Sci. Rep, vol.6, p.21664, 2016. ,
Functional expression of the renin-angiotensin system in human podocytes, Am. J. Physiol. Renal Physiol, vol.290, issue.3, pp.710-719, 2006. ,
Vitamin D receptor signaling in podocytes protects against diabetic nephropathy, J. Am. Soc. Nephrol, vol.23, issue.12, pp.1977-1986, 2012. ,
Actin dynamics at focal adhesions: a common endpoint and putative therapeutic target for proteinuric kidney diseases, Kidney Int, vol.93, issue.6, pp.1298-1307, 2018. ,
A review of podocyte biology, Am. J. Nephrol, vol.47, issue.1, pp.3-13, 2018. ,
Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis, Kidney Blood Press Res, vol.31, issue.2, pp.111-121, 2008. ,
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells, Cell Metab, vol.15, issue.2, pp.186-200, 2012. ,
Synaptopodin protects against proteinuria by disrupting Cdc 42:IRSp53: Mena signaling complexes in kidney podocytes, Am. J. Pathol, vol.171, issue.2, pp.415-427, 2007. ,
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis, Nat. Med, vol.25, issue.8, pp.1280-1289, 2019. ,
Determination of primary versus secondary membranous glomerulopathy utilizing phospholipase A2 receptor staining in renal biopsies, Mod. Pathol, vol.26, issue.5, pp.709-715, 2013. ,
Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines, Exp Cell Res, vol.236, issue.1, pp.248-258, 1997. ,
KIBRA modulates directional migration of podocytes, J. Am. Soc. Nephrol, vol.19, issue.10, pp.1891-1903, 2008. ,
Notch2 activation ameliorates nephrosis, Nat. Commun, vol.5, p.3296, 2014. ,