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Attributable Mortality of Hip Fracture in Older Patients: A Retrospective Observational Study

Abstract : Hip fracture (HF) in older patients is associated with a high six-month mortality rate. Several clinical conditions may affect outcome, including baseline characteristics, co-existing acute illnesses, perioperative factors, and postoperative complications. Our primary objective was to estimate the respective effect of these four domains on six-month mortality after HF. A retrospective observational study using a monocentric cohort of older patients was conducted. All patients ≥ 70 years old admitted to the emergency department for HF and hospitalized in our perioperative geriatric care unit from June 2009 to September 2018 were included. Among 1015 included patients, five (0.5%) were lost to follow-up, and 1010 were retained in the final analysis (mean age 86 ± 6 years). The six-month mortality rate was 14.8%. The six-month attributable mortality estimates were as follows: baseline characteristics (including age, gender, comorbidities, autonomy, type of fracture): 62.4%; co-existing acute illnesses (including acute events present before surgery that could result from the fracture or cause it): 0% (not significantly associated with six-month mortality); perioperative factors (including blood transfusion and delayed surgery): 12.3%; severe postoperative complications: 11.9%. Baseline characteristics explained less than two-thirds of the six-month mortality after HF. Optimizing patients care by improving management of perioperative factors and thus decreasing postoperative complications, could reduce by a maximum of one quarter of the six-month mortality rate after HF.
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Submitted on : Wednesday, September 16, 2020 - 12:48:04 PM
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Lorène Zerah, David Hajage, Mathieu Raux, Judith Cohen-Bittan, Anthony Mézière, et al.. Attributable Mortality of Hip Fracture in Older Patients: A Retrospective Observational Study. Journal of Clinical Medicine, MDPI, 2020, 9 (8), pp.2370. ⟨10.3390/jcm9082370⟩. ⟨hal-02940509⟩

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