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Comparison of Iron Oxide Nanoparticles in Photothermia and Magnetic Hyperthermia: Effects of Clustering and Silica Encapsulation on Nanoparticles' Heating Yield

Abstract : Superparamagnetic iron oxide nanoparticles (SPIONs) have a recognized potential for magnetic hyperthermia, and they are also being increasingly proposed as agents for photothermal treatment (photothermia), a biomedical modality where nanoparticles are excited by light to generate local hyperthermia. While it is known that endosomal internalization of SPIONs negatively affects magnetic hyperthermia, photothermia is not decreased. In an attempt to mimic nanoparticles clustering in endosomes, we herein investigate the effects of silica encapsulation and SPION clustering on both magnetic hyperthermia and photothermia.
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https://hal.sorbonne-universite.fr/hal-03018680
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Submitted on : Monday, November 23, 2020 - 9:11:04 AM
Last modification on : Thursday, April 15, 2021 - 3:08:14 PM
Long-term archiving on: : Wednesday, February 24, 2021 - 6:23:32 PM

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Sebastjan Nemec, Slavko Kralj, Claire Wilhelm, Ali Abou-Hassan, Marie-Pierre Rols, et al.. Comparison of Iron Oxide Nanoparticles in Photothermia and Magnetic Hyperthermia: Effects of Clustering and Silica Encapsulation on Nanoparticles' Heating Yield. Applied Sciences, MDPI, 2020, 10 (20), pp.7322. ⟨10.3390/app10207322⟩. ⟨hal-03018680⟩

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