Skip to Main content Skip to Navigation
Journal articles

Women and Diabetes: Preventing Heart Disease in a New Era of Therapies

Abstract : Despite major advances in cardiovascular research over the past decade, women with type 2 diabetes have a high risk of cardiovascular events. Several factors contribute to the poor prognosis for women, including higher levels of frailty and comorbidities, but their cardiovascular risk is underestimated and there is suboptimal implementation and uptitration of new evidence-based therapies, leading to high morbidity and mortality. Recent studies highlight the need for better management of diabetes in women that can be pursued and achieved in light of recent results from randomised controlled trials demonstrating evidence of the benefits of new therapeutic strategies in improving cardiovascular outcomes and quality of life of women covering the entire cardiovascular continuum. This review critically discusses the multiple benefits for women of new pharmacological treatments, such as glucagon-like peptide-1 receptor agonists, sodium–glucose cotransporter type 2 inhibitors (SGLT2i), proprotein convertase subtilisin/kexin type 9 inhibitors, inclisiran, icosapent ethyl and bempedoic acid in preventing cardiovascular events, and treatments, such as angiotensin receptor neprilysin inhibitors, SGLT2i, vericiguat and omecamtiv mecarbil, for preventing heart failure.
Document type :
Journal articles
Complete list of metadata

https://hal.sorbonne-universite.fr/hal-03448583
Contributor : Gestionnaire Hal-Su Connect in order to contact the contributor
Submitted on : Thursday, November 25, 2021 - 11:27:47 AM
Last modification on : Friday, December 3, 2021 - 12:13:15 PM

File

ECR_Galati_WEB.pdf
Publication funded by an institution

Identifiers

Collections

Citation

Giuseppe Galati, Pierre Sabouret, Olga Germanova, Deepak Bhatt. Women and Diabetes: Preventing Heart Disease in a New Era of Therapies. European Cardiology Review, Radcliffe Medical Press Lmd, 2021, 16, ⟨10.15420/ecr.2021.22⟩. ⟨hal-03448583⟩

Share

Metrics

Record views

12

Files downloads

10