Objective An electronic surveillance system was released to monitor morbidity and mortality incidence of imported malaria cases, investigate autochthonous cases, and assess chemosensitivity of Plasmodium isolates among travelers to and from endemic areas. The aim of this study is to evaluate the use of an electronic surveillance system for imported malaria in France. Materials and Methods Three main indicators were used to assess the online malaria web-based surveillance system: (1) the quality of the surveillance system; (2) the capacity of the online system to early warning in case of particular events of public health; (3) the knowledge, attitude, and practice of online electronic system by practitioners of malaria network in France. Results Overall, the median time onset a case is reported to the system decrease by 99%, ranging from 227 days (144–309) to 2 days (1–6) in 2006 and 2020, respectively. Conclusion The online malaria surveillance system in France has demonstrated its effectiveness and can therefore be extended to carry out numerous investigations linked to research on malaria.