H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice.
Keywords
*Transcriptome
Animals
Cytokines/genetics/physiology
Female
Humans
Influenza A Virus
H1N1 Subtype/pathogenicity/*physiology
H5N1 Subtype/pathogenicity/*physiology
H7N7 Subtype/pathogenicity/*physiology
H7N9 Subtype/pathogenicity/*physiology
Influenza
Human/*genetics/metabolism/mortality/virology
Male
Mice
Inbred BALB C
Virulence