Benchmarking of T-cell receptor repertoire profiling methods reveals large systematic biases - Sorbonne Université Access content directly
Conference Papers Year : 2019

Benchmarking of T-cell receptor repertoire profiling methods reveals large systematic biases

Abstract

With the advances in next-generation sequencing and data modelling, T-cell receptor and B-cell repertoires are now believed to provide biomarkers of disease and diagnostics in several immune related diseases as well as new tools for the development of new therapeutic targets. In the race of methods development, it is important to ensure the reliability of such complex biological component characterized by an uneven diversity. During this seminar, Encarnita Mariotti-Ferrandiz will her introduce recent comparative study that evaluated the performances of various molecular biology methods commonly used in the field for T-cell receptor repertoire study. Anne Eugster will further introduce plans from the AIRR-Community Biological Resources working group regarding B-cell receptor benchmarking.
No file

Dates and versions

hal-03977244 , version 1 (07-02-2023)

Identifiers

  • HAL Id : hal-03977244 , version 1

Cite

Encarnita Mariotti-Ferrandiz. Benchmarking of T-cell receptor repertoire profiling methods reveals large systematic biases. iReceptorPlus Seminar Series, iReceptorPlus Consortium, Jan 2019, Tel Aviv, Israel. ⟨hal-03977244⟩
7 View
0 Download

Share

Gmail Mastodon Facebook X LinkedIn More