[Exposure to fine air particles and occurrence of allergic diseases: results of ISAAC-France phase 2]. - Sorbonne Université Access content directly
Journal Articles Archives de Pédiatrie Year : 2009

[Exposure to fine air particles and occurrence of allergic diseases: results of ISAAC-France phase 2].

D. Caillaud
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François Lavaud
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A. Taytard
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G. Pauli
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D. Charpin
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Abstract

To evaluate whether fine air particles could be involved in the occurrence of atopy and allergic diseases, we performed a cross-sectional epidemiological survey involving primary schoolchildren living in six French towns with contrasted air pollution levels. Air pollution was measured during a week in the school yards and by standard air monitoring networks. Children get an examination in school looking for atopic dermatitis and bronchial hyperresponsiveness assessed by a standardized run test. Besides, parents or guardians provided past medical history and environmental data, especially on passive smoking. Overall, 5,338 children, aged 10.4 (+/-0.7) years, coming from 108 different schools and 401 different classes were included in the survey. Taking into account potential confounders, high exposure to proximity PM(2.5) was linked to a higher point prevalence of atopic dermatitis and hyperresponsiveness, to a higher cumulative prevalence of allergic asthma and a higher sensitization rate to common indoor allergens. Thus, these data suggest that chronic exposure to urban fine particles could be a risk factor for atopy, hyperresponsiveness and asthma.

Dates and versions

hal-00595449 , version 1 (24-05-2011)

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Isabella Annesi-Maesano, D. Caillaud, François Lavaud, D. Moreau, Y. Le Moullec, et al.. [Exposure to fine air particles and occurrence of allergic diseases: results of ISAAC-France phase 2].. Archives de Pédiatrie, 2009, 16 (3), pp.299-305. ⟨10.1016/j.arcped.2008.12.004⟩. ⟨hal-00595449⟩
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