[A prospective study of quality of life and treatment of chemotherapy-induced anaemia in lung cancer]. - Sorbonne Université Access content directly
Journal Articles Revue des Maladies Respiratoires Year : 2007

[A prospective study of quality of life and treatment of chemotherapy-induced anaemia in lung cancer].

I. Borget
  • Function : Author
P. Tilleul
  • Function : Author
M. Baud
  • Function : Author
A. Granghaud
  • Function : Author
E. Iglesias
  • Function : Author

Abstract

INTRODUCTION: The impact of chemotherapy-induced anemia on the quality of life (QOL) of patients with lung cancer has been little studied. OBJECTIVE: We evaluated the feasibility of measuring QOL among patients receiving chemotherapy for lung cancer, and the possible correlation of QOL with the haemoglobin level. METHODS: This was a prospective study of 53 patients starting chemotherapy (total 155 cycles); QOL was measured with the specific Fact-An scale. RESULTS: The mean haemoglobin level before treatment was 13.1+/-2.3 g/dl. During chemotherapy 45.3% of patients received erythrocytic growth factors and 15.1% were transfused; 26.4% of patients refused to answer or could not answer the QOL questionnaire. There was a strong correlation between the Hb level and overall QOL (r=0.343, p=0.0004), as well as the physical and functional subscales (but not the cognitive and social subscales). CONCLUSIONS: Although QOL could not be measured in one-quarter of cases, it was clearly affected by anaemia, which supports a strategy of early diagnosis and management of anaemia due to chemotherapy for lung cancer.
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Dates and versions

hal-00597137 , version 1 (31-05-2011)

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  • HAL Id : hal-00597137 , version 1
  • PUBMED : 17268364

Cite

I. Borget, P. Tilleul, M. Baud, A. Granghaud, E. Iglesias, et al.. [A prospective study of quality of life and treatment of chemotherapy-induced anaemia in lung cancer].. Revue des Maladies Respiratoires, 2007, 24 (1), pp.41-7. ⟨hal-00597137⟩
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