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Article Dans Une Revue Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference Année : 2007

MDRView: a visualization of the polymorphisms of MDR1(ABCB1) GENE in breast cancer.

Résumé

This paper presents the Generalized CaseView method applied to the study of polymorphisms of MDR1 (Multi Drug Resistant), a gene coding for a trans-membrane transporting protein. The data base contains Single nucleotide polymorphisms, their positions in cDNA, and the Area Under the Curve of drugs concentrations. The generalized CaseView method permits a compact visualization of these data. The main result is that pharmacokinetics of some anticancer drugs depends on the genotype.
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Dates et versions

hal-00597682 , version 1 (01-06-2011)

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Edlira Xhemo, Anne Fajac, Jean-Yves Boire, Pierre Levy. MDRView: a visualization of the polymorphisms of MDR1(ABCB1) GENE in breast cancer.. Conference proceedings : .. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2007, 2007, pp.4592-4. ⟨10.1109/IEMBS.2007.4353362⟩. ⟨hal-00597682⟩
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