Calcium oxalate precipitation by diffusion using laminar microfluidics: toward a biomimetic model of pathological microcalcifications - Sorbonne Université Access content directly
Journal Articles Lab on a Chip Year : 2016

Calcium oxalate precipitation by diffusion using laminar microfluidics: toward a biomimetic model of pathological microcalcifications

Emmanuel Letavernier
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Michel Daudon
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V. Frochot
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Jean-Philippe Haymann
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  • PersonId : 956379

Abstract

The effect of mixing calcium and oxalate precursors by diffusion at miscible liquid interfaces on calcium oxalate crystalline phases, and in physiological conditions (concentrations and flow rates), is studied using a microfluidic channel. This channel has similar dimensions as the collection duct in human kidneys and serves as a biomimetic model in order to understand the formation of pathological microcalcifications.
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hal-01288757 , version 1 (31-03-2016)

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G. Laffite, César Leroy, Christian Bonhomme, L. Bonhomme-Coury, Emmanuel Letavernier, et al.. Calcium oxalate precipitation by diffusion using laminar microfluidics: toward a biomimetic model of pathological microcalcifications. Lab on a Chip, 2016, 16 (7), pp.1157-1160. ⟨10.1039/C6LC00197A⟩. ⟨hal-01288757⟩
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