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Synergistic role of calcium and vitamin D in a murine model of kidney stone disease

Abstract : The role of vitamin D in kidney stone formation remains controversial. We analyzed whether long-term exposure of rats to vitamin D supplementation, with or without calcium-rich diet, would promote kidney stone formation or kidney tissue calcifications. Four groups of rats received vitamin D alone (100,000 UI/Kg every 3 weeks), a calcium-enriched diet alone (calcium gluconate 2g/l in drinking water), both vitamin D supplementation and calcium rich diet, or a standard diet (controls) during 6 months. Serum and urine parameters and crystalluria have been monitored during 6 months
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https://hal.sorbonne-universite.fr/hal-01339324
Contributor : Gestionnaire Hal-Upmc <>
Submitted on : Wednesday, June 29, 2016 - 3:54:16 PM
Last modification on : Wednesday, October 14, 2020 - 4:12:39 AM

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  • HAL Id : hal-01339324, version 1

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Emmanuel Letavernier, Cécile Verrier, Florent Goussard, Léa Huguet, Jean-Philippe Haymann, et al.. Synergistic role of calcium and vitamin D in a murine model of kidney stone disease. 13th International Symposium on Urolithiasis, Jul 2016, Chiba, Japan. pp.O-14. ⟨hal-01339324⟩

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