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Journal articles
Design and Cellular Fate of Bioinspired Au–Ag Nanoshells@Hybrid Silica Nanoparticles
Samantha Soulé
1
Anne-Laure Bulteau
1
Stéphane Faucher
Bernard Haye
2
Carole Aimé
3
Joachim Allouche
1, *
Jean-Charles Dupin
1
Gaëtane Lespes
1
Thibaud Coradin
3
Hervé Martinez
1
*
Corresponding author
Samantha Soulé 1
Author IdHAL : samantha-soule
Anne-Laure Bulteau 1
Author
Stéphane Faucher
Author IdHAL : stephane-faucher ORCID : https://orcid.org/0000-0001-8887-6055
Bernard Haye 2
Author
Carole Aimé 3
Author IdHAL : carole-aime ResearcherId : http://www.researcherid.com/rid/Q-5328-2018
Joachim Allouche 1
Correspondent author IdHAL : joachim-allouche ORCID : https://orcid.org/0000-0002-0846-8009
Jean-Charles Dupin 1
Author IdHAL : jean-charles-dupin ORCID : https://orcid.org/0000-0002-5336-7629
Gaëtane Lespes 1
Author IdHAL : gaetane-lespes ORCID : https://orcid.org/0000-0002-1752-8923
Thibaud Coradin 3
Author IdHAL : thibaud-coradin ORCID : https://orcid.org/0000-0003-3374-5722
Hervé Martinez 1
Author IdHAL : herve-martinez IdRef : https://www.idref.fr/060274883
1
IPREM - Institut des sciences analytiques et de physico-chimie pour l'environnement et les materiaux (UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR, Hélioparc Pau Pyrénées, 2 avenue du Président Angot, 64053 PAU CEDEX 9 - France)
- UPPA - Université de Pau et des Pays de l'Adour (Avenue de l'Université - BP 576 - 64012 Pau Cedex - France)
- CNRS - Centre National de la Recherche Scientifique : UMR5254 (France)
2
LCMCP - Laboratoire de Chimie de la Matière Condensée de Paris (11 place Marcelin Berthelot 75231 Paris Cedex 05 - France)
- CNRS - Centre National de la Recherche Scientifique : UMR7574 (France)
- UPMC - Université Pierre et Marie Curie - Paris 6 (4 place Jussieu - 75005 Paris - France)
- CdF (institution) - Collège de France (France)
3
MATBIO - Matériaux et Biologie (France)
- LCMCP - Laboratoire de Chimie de la Matière Condensée de Paris (11 place Marcelin Berthelot 75231 Paris Cedex 05 - France)
- CNRS - Centre National de la Recherche Scientifique : UMR7574 (France)
- UPMC - Université Pierre et Marie Curie - Paris 6 (4 place Jussieu - 75005 Paris - France)
- CdF (institution) - Collège de France (France)
Abstract : Silica-coated gold–silver alloy nanoshells were obtained via a bioinspired approach using gelatin and poly-l-lysine (PLL) as biotemplates for the interfacial condensation of sodium silicate solutions. X-ray photoelectron spectroscopy was used as an efficient tool for the in-depth and complete characterization of the chemical features of nanoparticles during the whole synthetic process. Cytotoxicity assays using HaCaT cells evidenced the detrimental effect of the gelatin nanocoating and significant induction of late apoptosis after silicification. In contrast, PLL-modified nanoparticles had less biological impact that was further improved by the silica layer, and uptake rates of up to 50% of those of the initial particles could be achieved. These results are discussed considering the effect of nanosurface confinement of the biopolymers on their chemical and biological reactivity.
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Journal articles
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https://hal.sorbonne-universite.fr/hal-01475846
Contributor : Gestionnaire Hal-Upmc <>
Submitted on : Friday, February 24, 2017 - 11:34:20 AM
Last modification on : Tuesday, February 2, 2021 - 2:58:03 PM
Contributor : Gestionnaire Hal-Upmc <>
Submitted on : Friday, February 24, 2017 - 11:34:20 AM
Last modification on : Tuesday, February 2, 2021 - 2:58:03 PM
Identifiers
- HAL Id : hal-01475846, version 1
- DOI : 10.1021/acs.langmuir.6b02810
Collections
UPMC | CNRS | UNIV-PAU | LCMCP | CDF | LCMCP-MATBIO | INC-CNRS | IPREM | IPREM-CME | SORBONNE-UNIVERSITE | SU-SCIENCES | IPREM-PCM | PSL
Citation
Samantha Soulé, Anne-Laure Bulteau, Stéphane Faucher, Bernard Haye, Carole Aimé, et al.. Design and Cellular Fate of Bioinspired Au–Ag Nanoshells@Hybrid Silica Nanoparticles. Langmuir, American Chemical Society, 2016, 32 (39), pp.10073 - 10082. ⟨10.1021/acs.langmuir.6b02810⟩. ⟨hal-01475846⟩
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