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Journal Articles Oxidative Medicine and Cellular Longevity Year : 2016

Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016

Abstract

Oxidative stress (OS) is an imbalance between the formation of reactive oxygen species (ROS) and antioxidant defense mechanisms. This phenomenon increases with age and affects the normal functioning of several tissues. Furthermore, numerous chronic diseases associated with older age, such as diabetes and cardiovascular, renal, pulmonary, and skeletal muscle disorders, are also directly related to OS. Considering this relationship, the aim of many ongoing studies is to elucidate the underlying mechanisms and role of OS in disease onset and development. In particular, there is considerable emphasis on finding new therapeutic strategies for decreasing OS.
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hal-01485278 , version 1 (08-03-2017)

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Claudio Cabello-Verrugio, Felipe Simon, Capucine Trollet, Juan F. Santibañez. Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016. Oxidative Medicine and Cellular Longevity, 2016, 2017, pp.4310469. ⟨10.1155/2017/4310469⟩. ⟨hal-01485278⟩
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