Traveling Wave and Aggregation in a Flux-Limited Keller-Segel Model

Vincent Calvez 1, 2 Benoît Perthame 3, 4 Shugo Yasuda 5
2 NUMED - Numerical Medicine
UMPA-ENSL - Unité de Mathématiques Pures et Appliquées, Inria Grenoble - Rhône-Alpes
4 MAMBA - Modelling and Analysis for Medical and Biological Applications
Inria de Paris, LJLL (UMR_7598) - Laboratoire Jacques-Louis Lions
Abstract : Flux-limited Keller-Segel (FLKS) model has been recently derived from kinetic transport models for bacterial chemotaxis and shown to represent better the collective movement observed experimentally. Recently, associated to the kinetic model, a new instability formalism has been discovered related to stiff chemotactic response. This motivates our study of traveling wave and aggregation in population dynamics of chemotactic cells based on the FLKS model with a population growth term. Our study includes both numerical and theoretical contributions. In the numerical part, we uncover a variety of solution types in the one-dimensional FLKS model additionally to standard Fisher/KPP type traveling wave. The remarkable result is a counter-intuitive backward traveling wave, where the population density initially saturated in a stable state transits toward an unstable state in the local population dynamics. Unexpectedly, we also find that the backward traveling wave solution transits to a localized spiky solution as increasing the stiffness of chemotactic response. In the theoretical part, we obtain a novel analytic formula for the minimum traveling speed which includes the counterbalancing effect of chemotactic drift vs. reproduction/diffusion in the propagating front. The front propagation speeds of numerical results only slightly deviate from the minimum traveling speeds, except for the localized spiky solutions, even for the backward traveling waves. We also discover an analytic solution of unimodal traveling wave in the large-stiffness limit, which is certainly unstable but exists in a certain range of parameters.
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Submitted on : Thursday, September 21, 2017 - 2:34:34 PM
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Vincent Calvez, Benoît Perthame, Shugo Yasuda. Traveling Wave and Aggregation in a Flux-Limited Keller-Segel Model. Kinetic and Related Models , AIMS, 2018, 11 (4), pp.891-909. ⟨10.3934/krm.2018035⟩. ⟨hal-01591490⟩

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