Skip to Main content Skip to Navigation
Journal articles

Eosin-mediated synthesis of polymer coatings combining photodynamic inactivation and antimicrobial properties

Abstract : Polymer coatings exhibiting photodynamic bacterial inactivation properties have been successfully engineered. Such coatings were obtained by photoinduced crosslinking of a PEG-diacrylate monomer associated with the eosin Y dye which was used as both a radical photoinitiator and an antibacterial agent. A dual curing process was followed by combining compatible and solvent-free polymerization mechanisms, i.e. Aza-Michael reaction and free-radical polymerization in the presence of amines. The kinetics evolution of the photopolymerization process was followed using in situ Fourier transform infrared spectroscopy, allowing for the elucidation of the underlying mechanistic pathways. The influence of eosin Y and amines on the thermal and mechanical properties of the films was evidenced and discussed in terms of crosslinking chemistry. The antibacterial properties of the coatings against two different strains (Escherichia coli and Staphylococcus aureus) were evaluated on short and long terms, revealing that eosin confers both photodynamic inactivation and antimicrobial properties to the films. These coatings are therefore particularly promising for disposable medical devices.
Document type :
Journal articles
Complete list of metadatas

Cited literature [62 references]  Display  Hide  Download

https://hal.sorbonne-universite.fr/hal-02121246
Contributor : Lea Trichet <>
Submitted on : Wednesday, July 10, 2019 - 11:18:07 AM
Last modification on : Saturday, April 11, 2020 - 2:13:52 AM

File

3-2017 sautrot-bas_sans marque...
Files produced by the author(s)

Identifiers

Citation

P. Sautrot-Ba, A. Contreras, S Andaloussi, T. Coradin, C. Hélary, et al.. Eosin-mediated synthesis of polymer coatings combining photodynamic inactivation and antimicrobial properties. Journal of materials chemistry‎ B, Royal Society of Chemistry, 2017, 5 (36), pp.7572-7582. ⟨10.1039/c7tb01358b⟩. ⟨hal-02121246⟩

Share

Metrics

Record views

109

Files downloads

226