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Journal Articles Journal of Colloid and Interface Science Year : 2018

Layer-by-layer assembly of brushes of vertically-standing enzymatic nanotubes

Abstract

Brushes of vertically-standing enzyme-containing nanotubes are prepared onto planar surfaces by a combination of hard-templating and layer-by-layer assembly. The nanotubes have a core-shell morphology made of two compartments, one for mechanical rigidity, the other containing b-lactamase for bioactivity. We demonstrate inclusion of the enzymatic component either in the core or in the shell part of the nanotubes. Kinetic studies reveal that both types of systems are bioactive but that the activity is significantly better preserved over long time periods when b-lactamase is incorporated in the core of the nanotubes.
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Dates and versions

hal-02144948 , version 1 (31-05-2019)

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Diana G. Ramírez-Wong, Christian Bonhomme, Sophie Demoustier-Champagne, Alain M. Jonas. Layer-by-layer assembly of brushes of vertically-standing enzymatic nanotubes. Journal of Colloid and Interface Science, 2018, 514, pp.592-598. ⟨10.1016/j.jcis.2017.12.063⟩. ⟨hal-02144948⟩
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