Skip to Main content Skip to Navigation
Journal articles

Target Of Rapamycin pathway in the white-rot fungus Phanerochaete chrysosporium

Abstract : The Target Of Rapamycin (TOR) signaling pathway is known to regulate growth in response to nutrient availability and stress in eukaryotic cells. In the present study, we have investigated the TOR pathway in the white-rot fungus Phanerochaete chrysosporium. Inhibition of TOR activity by rapamycin affects conidia germination and hyphal growth highlighting the conserved mechanism of susceptibility to rapamycin. Interestingly, the secreted protein content is also affected by the rapamycin treatment. Finally, homologs of the components of TOR pathway can be identified in P. chrysosporium. Altogether, those results indicate that the TOR pathway of P. chrysosporium plays a central role in this fungus.
Document type :
Journal articles
Complete list of metadata

Cited literature [34 references]  Display  Hide  Download

https://hal.sorbonne-universite.fr/hal-02797241
Contributor : Gestionnaire Hal-Su <>
Submitted on : Friday, June 5, 2020 - 2:37:28 PM
Last modification on : Thursday, March 4, 2021 - 9:44:01 AM

File

journal.pone.0224776.pdf
Publication funded by an institution

Identifiers

Citation

Duy Vuong Nguyen, Thomas Roret, Antonio Fernandez-Gonzalez, Annegret Kohler, Melanie Morel-Rouhier, et al.. Target Of Rapamycin pathway in the white-rot fungus Phanerochaete chrysosporium. PLoS ONE, Public Library of Science, 2020, 15 (2), pp.e0224776. ⟨10.1371/journal.pone.0224776⟩. ⟨hal-02797241⟩

Share

Metrics

Record views

67

Files downloads

64