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Article Dans Une Revue Journal of Clinical Medicine Année : 2020

High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis

Laurent Rosier
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Amir Zouaghi
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Eloi Marijon
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Nicolas Sadoul
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Samuel Chauveau
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Michael Peyrol
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Jérémie Barraud
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Vincent Algalarrondo
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Estelle Gandjbakhch

Résumé

Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patients. We sought to assess the risk of major arrhythmic ventricular events (MAEs) over time in patients implanted with an ICD following sustained VT/VF in the acute phase of myocarditis compared to those implanted for VT/VF occurring on myocarditis sequelae. Our retrospective observational study included patients implanted with an ICD following VT/VF during acute myocarditis or VT/VF on myocarditis sequelae, from 2007 to 2017, in 15 French university hospitals. Over a median follow-up period of 3 years, MAE occurred in 11 (39%) patients of the acute myocarditis group and 24 (60%) patients of the myocarditis sequelae group. Kaplan-Meier MAE rate estimates at one and three years of follow-up were 19% and 45% in the acute group, and 43% and 64% in the sequelae group. Patients who experienced sustained ventricular arrhythmias during acute myocarditis had a very high risk of VT/VF recurrence during follow-up. These results show that the risk of MAE recurrence remains high after resolution of the acute episode.
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Dates et versions

hal-02949270 , version 1 (25-09-2020)

Identifiants

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Laurent Rosier, Amir Zouaghi, Valentin Barré, Raphaël Martins, Vincent Probst, et al.. High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis. Journal of Clinical Medicine, 2020, 9 (3), pp.848. ⟨10.3390/jcm9030848⟩. ⟨hal-02949270⟩
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