Numerical simulation of long term orthodontic tooth movement could help clinicians to plan more efficient and mechanically sound treatments (Burstone 2015). It remains a challenge and no prospective model exists yet. Finite element analysis (FEA) has been used by several authors to perform such simulations, but these studies usually lack of experimental calibration or validation (Schneider et al. 2002; Kojima and Fukui 2012; Chen et al. 2014). Moreover, a proper definition of the boundary conditions of the model is a critical issue as most of the orthodontic forces are statically indeterminate (Hamanaka et al. 2017). Our main objective was to perform a numerical study of orthodontic tooth displacement based on precise clinical data. We collected monthly three-dimensional (3D) displacement data of two canines submitted to a known force system. Then, we calibrated a preliminary patient-specific FEA model from these acquisitions.