Intracellular location matters: rationalization of the anti-inflammatory activity of a manganese( ii ) superoxide dismutase mimic complex
Résumé
A conjugate of a Mn-based superoxide dismutase mimic with a Re-based multimodal probe 1[combining low line] was studied in a cellular model of oxidative stress. Its speciation was investigated using Re and Mn X-fluorescence. Interestingly, 1[combining low line] shows a distribution different from its unconjugated analogue but a similar concentration in mitochondria and a similar bioactivity.
Domaines
Chimie
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Mathieu et al. - 2020 - Intracellular location matters rationalization of.pdf (3.29 Mo)
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