Disparities in Healthcare in Psoriatic Arthritis: An Analysis of 439 Patients from 13 Countries - Sorbonne Université Access content directly
Journal Articles RMD Open Year : 2022

Disparities in Healthcare in Psoriatic Arthritis: An Analysis of 439 Patients from 13 Countries

Ying Ying Leung
  • Function : Author
Martin Soubrier
Lihi Eder
  • Function : Author
Inna Gaydukova
  • Function : Author
Elaine Husni
  • Function : Author
Maarten De Wit
  • Function : Author

Abstract

Objectives Patient care can vary substantially by country. The objective was to explore differences in psoriatic arthritis (PsA) across countries for disease activity, impact and treatments. Methods A cross-sectional analysis of 13 countries from the Remission/Flare in PsA study ( NCT03119805 ) of consecutive adult patients with definite PsA was performed. Countries were classified into tertiles by gross domestic product (GDP)/capita. Disease activity (Disease Activity in PsA, DAPSA and Minimal Disease Activity, MDA) and their components, disease impact (patient-reported outcomes) and biological disease-modifying antirheumatic drugs (bDMARDs) were analysed per country and compared between the three tertiles of GDP/capita by parametric and non-parametric tests. We also explored the percentage of patients with significant disease activity (DAPSA >14) and no ongoing bDMARD prescription. Results In 439 patients (50.6% male, mean age 52.3 years, mean disease duration 10.1 years), disease activity and disease impact were higher in the lowest GDP/capita countries. DAPSA remission and MDA were attained in the lowest tertile in 7.0% and 18.4% patients, vs 29.1% and 49.5% in the middle tertile and 16.8% and 41.3% in the high tertile, respectively (all p<0.001). bDMARDs use was similar in the tertiles (overall mean 61%). The overall rate of patients with DAPSA >14\,and no bDMARDs was 18.5%, and was higher in lower GDP/capita countries (p=0.004). Conclusion PsA patients from countries with the lowest GDP/capita, despite similar use of bDMARDs, were more likely to have high disease activity and worse disease impact. There is a need for more equity in healthcare.

Dates and versions

hal-03896044 , version 1 (13-12-2022)

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Florian Lucasson, Uta Kiltz, Umut Kalyoncu, Ying Ying Leung, Penelope Palominos, et al.. Disparities in Healthcare in Psoriatic Arthritis: An Analysis of 439 Patients from 13 Countries. RMD Open, 2022, 8 (1), pp.e002031. ⟨10.1136/rmdopen-2021-002031⟩. ⟨hal-03896044⟩
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