Letter: the use of magnetic resonance scores (Anali) for risk stratification in PSC - Sorbonne Université Access content directly
Journal Articles Alimentary Pharmacology & Therapeutics (Suppl) Year : 2021

Letter: the use of magnetic resonance scores (Anali) for risk stratification in PSC

Abstract

GBCA gadolinium-based contrast agent MR magnetic resonance MRC magnetic resonance cholangiography PSC primary sclerosing cholangitis VCTE vibration controlled transient elastography Dear editor, We read with interest the review written by Mahzar and Russo about non-invasive prognostic tests for primary sclerosing cholangitis (PSC) 1. Although rare, PSC is a serious disease, associated with potentially lethal complications, notably cirrhosis and cholangiocarcinoma 2. Liver transplantation is the only curative treatment for PSC and median transplant-free survival is approximately 12-21 years after diagnosis 3. Identification of prognostic factors is essential for tailoring the follow-up strategies and testing new therapeutic modalities in homogeneous groups of PSC patients. As detailed in this review, over the last twenty years, different teams across the world, including ours, have identified several noninvasive prognostic tests for PSC patients 1. First, our team demonstrated in a large retrospective study that liver stiffness measured by vibration-controlled transient elastography (VCTE) was an independent predictive marker of survival in PSC patients 4. Next, we built 2 magnetic resonance (MR) risk scores (with and without gadolinium-based contrast agent (GBCA) administration) 5 , called Anali scores, and showed that they were able to predict adverse outcome-free survival (defined by survival without liver transplantation or cirrhosis
Fichier principal
Vignette du fichier
letter APT.pdf (94.5 Ko) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

hal-03985305 , version 1 (13-02-2023)

Identifiers

Cite

Sara Lemoinne, Nora Cazzagon, Olivier Chazouillères, Christophe Corpechot, Lionel Arrivé. Letter: the use of magnetic resonance scores (Anali) for risk stratification in PSC. Alimentary Pharmacology & Therapeutics (Suppl), 2021, 53 (12), pp.1329-1330. ⟨10.1111/apt.16378⟩. ⟨hal-03985305⟩
4 View
19 Download

Altmetric

Share

Gmail Facebook X LinkedIn More