The understanding of coupled thermo-hydro-mechanical behaviour of fault zones or in naturally fractured reservoirs is essential both for fundamental and applied sciences and in particular for the safety assessment of radioactive waste disposal facilities. The overall objective of the CHENILLE project is to better understand the physical processes resulting from thermal and hydraulic loading in a small fault zone in a highly consolidated shale formation. Consequently, a thermally controlled in-situ fluid injection experiment is intended to be performed on a strike-slip fault zone outcropping at the Tournemire/France Underground Research Laboratory (URL). A heating system has been installed around the injection area to enable a precise and controlled incremental increase of the thermal load. Different monitoring systems are designed to measure the seismic and aseismic deformation induced either by thermal and/or by hydraulic loading. The seismic monitoring system is composed of Acoustic Emission (AE) and broadband seismic sensors enabling monitoring of seismic fracturing processes down to sub-decimetre scale as well as slow deformation processes. Furthermore, we are about to install an injection chamber allowing to perform a controlled gaz injection test. The injection borehole will also be partly equipped with fiber optics in order to measure temperature in a distributed manner in the borehole. Time-lapse active seismic surveys are scheduled for before and after the experiment to image the structural network but also to detect the appearance of new structures triggered from the hydro-thermal pressurization of the fault as well as eventual changes in the velocity field.