Compressibility and porosity modulate the mechanical properties of giant gas vesicles - Sorbonne Université Access content directly
Journal Articles Proceedings of the National Academy of Sciences of the United States of America Year : 2023

Compressibility and porosity modulate the mechanical properties of giant gas vesicles

Abstract

Significance Gas vesicles are produced in bacteria to achieve cellular buoyancy. These air-filled protein structures were the inspiration for developing a similar system to serve as contrast agents for ultrasound imaging. To characterize their mechanical properties, we study here the micropipette aspiration of giant gas vesicles formed by coating microbubbles with surface-active proteins adsorbed on their surface. We observe a variety of behaviors, such as large or remanent deformations. We extend current theoretical models of vesicle suction to compressible gas-filled systems and introduce the measurement of bubble permeability with this technique. We highlight the possibility of using engineered bubbles for echogenic applications and therapeutic techniques.
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Dates and versions

hal-04075445 , version 1 (20-04-2023)

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Hedar H Al-Terke, Grégory Beaune, Muhammad Junaid, Jani Seitsonen, Arja Paananen, et al.. Compressibility and porosity modulate the mechanical properties of giant gas vesicles. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (4), ⟨10.1073/pnas.2211509120⟩. ⟨hal-04075445⟩
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