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Journal Articles JAMA neurology Year : 2023

Advocating for Demonstration of Disease Modification—Have We Been Approaching Clinical Trials in Early Alzheimer Disease Incorrectly?

Abstract

This Viewpoint discusses the benefits of clinical trials with a delayed-start design and analysis of downstream biomarkers to examine whether antimyeloid immunotherapy changes the course of early Alzheimer disease.
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hal-04230862 , version 1 (06-10-2023)

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Vincent Planche, Nicolas Villain. Advocating for Demonstration of Disease Modification—Have We Been Approaching Clinical Trials in Early Alzheimer Disease Incorrectly?. JAMA neurology, 2023, 80 (7), pp.659. ⟨10.1001/jamaneurol.2023.0815⟩. ⟨hal-04230862⟩
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