Location specific rupture risk of intracranial aneurysms: case of ophthalmic aneurysms - Sorbonne Université Access content directly
Journal Articles Journal of Neurointerventional Surgery Year : 2023

Location specific rupture risk of intracranial aneurysms: case of ophthalmic aneurysms

Xavier Guerra
  • Function : Author
Jonathan Cortese
  • Function : Author
Julien Burel
  • Function : Author
Thomas Courret
Pacome Constant Dit Beaufils
  • Function : Author
Thibault Agripnidis
Ian Leonard-Lorant
  • Function : Author
Cédric Fauché
  • Function : Author
Nourou Dine Adeniran Bankole
Géraud Forestier
Vincent l'Allinec
Peter B Sporns
Gaelle Gueton
  • Function : Author
Nico Lorena
  • Function : Author
Marios-Nikos Psychogios
  • Function : Author
Jean-Baptiste Girot
  • Function : Author
Aymeric Rouchaud
Kevin Janot
Nicolas Raynaud
  • Function : Author
Raoul Pop
  • Function : Author
Jean-François Hak
Basile Kerleroux
Romain Bourcier
  • Function : Author
Gaultier Marnat
Chrysanthi Papagiannaki
Nader-Antoine Sourour
  • Function : Author
Frédéric Clarençon
Eimad Shotar
  • Function : Author

Abstract

Background Aneurysm location is a key element in predicting the rupture risk of an intracranial aneurysm. A common impression suggests that pure ophthalmic aneurysms are under-represented in ruptured intracranial aneurysms (RIAs). The purpose of this study was to specifically evaluate the risk of rupture of ophthalmic aneurysms compared with other aneurysm locations. Methods This multicenter study compared the frequency of ophthalmic aneurysms in a prospective cohort of RIAs admitted to 13 neuroradiology centers between January 2021 and March 2021, with a retrospective cohort of patients with unruptured intracranial aneurysms (UIAs) who underwent cerebral angiography at the same neuroradiology centers during the same time period. Results 604 intracranial aneurysms were included in this study (355 UIAs and 249 RIAs; mean age 57 years (IQR 49–65); women 309/486, 64%). Mean aneurysm size was 6.0 mm (5.3 mm for UIAs, 7.0 mm for RIAs; P<0.0001). Aneurysm shape was irregular for 37% UIAs and 73% RIAs (P<0.0001). Ophthalmic aneurysms frequency was 14.9% of UIAs (second most common aneurysm location) and 1.2% of RIAs (second least common aneurysm location; OR 0.07 (95% CI 0.02 to 0.23), P<0.0001). Conclusions Ophthalmic aneurysms seem to have a low risk of rupture compared with other intracranial aneurysm locations. This calls for a re-evaluation of the benefit–risk balance when considering preventive treatment for ophthalmic aneurysms.

Domains

Surgery
Fichier principal
Vignette du fichier
Manuscript v3 - Editor Copy.pdf (422.57 Ko) Télécharger le fichier
Fig1.jpg (247.38 Ko) Télécharger le fichier
Fig2_v3(2).jpg (582.23 Ko) Télécharger le fichier
Fig3_v4(1).jpg (1.77 Mo) Télécharger le fichier
Supplemental Figures.pdf (213 Ko) Télécharger le fichier
Supplemental Table.pdf (149.97 Ko) Télécharger le fichier
Origin Files produced by the author(s)
Licence
Origin Files produced by the author(s)

Dates and versions

hal-04406985 , version 1 (19-01-2024)

Licence

Identifiers

Cite

Pierre-Marie Chiaroni, Xavier Guerra, Jonathan Cortese, Julien Burel, Thomas Courret, et al.. Location specific rupture risk of intracranial aneurysms: case of ophthalmic aneurysms. Journal of Neurointerventional Surgery, 2023, pp.jnis-2023-020909. ⟨10.1136/jnis-2023-020909⟩. ⟨hal-04406985⟩
2 View
3 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More