The apical 70-pS K + channel in the thick ascending limb of Henle’s loop is a large-conductance Na + -and Cl – -activated, K Na 1.1-like, channel - Sorbonne Université Access content directly
Journal Articles American Journal of Physiology. Renal Physiology Year : 2024

The apical 70-pS K + channel in the thick ascending limb of Henle’s loop is a large-conductance Na + -and Cl – -activated, K Na 1.1-like, channel

Le canal potassique de 70 pS sur la membrane apicale de la branche large ascendante de l'anse de Henle est un canal de grande conductance, activé par le Na+ et le Cl- ressemblant à un canal KNa1.1.

Abstract

This study highlights new regulatory and conductive properties of the as yet poorly molecularly defined 70-pS K + channel in the apical membrane of the thick ascending limb of Henle’s loop cells of the mouse kidney that functionally identify it as a large-conductance, Na + - and Cl – -activated K Na 1.1-like channel.
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Wednesday, September 4, 2024
Embargoed file
Wednesday, September 4, 2024
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Dates and versions

hal-04556454 , version 1 (23-04-2024)

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Elise de Combiens, Nadia Frachon, Lydie Cheval, Stéphane Lourdel, Marc Paulais. The apical 70-pS K + channel in the thick ascending limb of Henle’s loop is a large-conductance Na + -and Cl – -activated, K Na 1.1-like, channel. American Journal of Physiology. Renal Physiology, 2024, 326 (3), pp.F485-F496. ⟨10.1152/ajprenal.00311.2023⟩. ⟨hal-04556454⟩
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