The apical 70-pS K + channel in the thick ascending limb of Henle’s loop is a large-conductance Na + -and Cl – -activated, K Na 1.1-like, channel
Le canal potassique de 70 pS sur la membrane apicale de la branche large ascendante de l'anse de Henle est un canal de grande conductance, activé par le Na+ et le Cl- ressemblant à un canal KNa1.1.
Résumé
This study highlights new regulatory and conductive properties of the as yet poorly molecularly defined 70-pS K + channel in the apical membrane of the thick ascending limb of Henle’s loop cells of the mouse kidney that functionally identify it as a large-conductance, Na + - and Cl – -activated K Na 1.1-like channel.