The laws of gravitation have been tested for a long time with steadily improving precision, leading at some moment of time to paradigmatic evolutions. Pursuing this continual effort is of great importance for science. In this communication, we focus on Solar System tests of gravity and more precisely on possible tests that can be performed with radio science observations (Range and Doppler). After briefly reviewing the current tests of gravitation at Solar System scales, we give motivations to continue such experiments. In order to obtain signature and estimate the amplitude of anomalous signals that could show up in radio science observables because of modified gravitational laws, we developed a new software that simulates Range/Doppler signals. We present this new tool that simulates radio science observables directly from the space-time metric. We apply this tool to the Cassini mission during its cruise from Jupiter to Saturn and derive constraints on the parameters entering alternative theories of gravity beyond the standard Parametrized Post Newtonian theory.