Surface plasmon resonance biosensors incorporating gold nanoparticles. - Sorbonne Université Access content directly
Journal Articles Macromolecular Bioscience Year : 2012

Surface plasmon resonance biosensors incorporating gold nanoparticles.

Abstract

SPR biosensing is increasingly popular for the detection of a multitude of biomolecules. It offers label-free detection and study of proteins, nucleic acids, and other biomolecules in real time. A recent trend involves incorporation of AuNPs, either within the sensing surface itself or as signal enhancing tagging molecules. The importance of AuNP and detecting agent spacing is described and techniques using macromolecular spacing aids are highlighted. Recent methods to enhance SPR detection capabilities using gold nanoparticles are reviewed, as well as device fabrication and the results of incorporation. SPR detection is a highly versatile method for the detection of biomolecules and, with the incorporation of AuNPs, shows promise in extending it to a number of new applications.

Dates and versions

hal-00745836 , version 1 (26-10-2012)

Identifiers

Cite

Erin Bedford, Jolanda Spadavecchia, Claire-Marie Pradier, Frank Gu. Surface plasmon resonance biosensors incorporating gold nanoparticles.. Macromolecular Bioscience, 2012, 12, pp.724-739. ⟨10.1002/mabi.201100435⟩. ⟨hal-00745836⟩
49 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More