Transition-Metal-Free Catalysts for the Sustainable Epoxidation of Alkenes: From Discovery to Optimisation by Means of High Throughput Experimentation - Sorbonne Université Access content directly
Journal Articles Combinatorial Chemistry and High Throughput Screening Year : 2012

Transition-Metal-Free Catalysts for the Sustainable Epoxidation of Alkenes: From Discovery to Optimisation by Means of High Throughput Experimentation

Abstract

Abstract: Transition-metal-free oxides were studied as heterogeneous catalysts for the sustainable epoxidation of alkenes with aqueous H2O2 by means of high throughput experimentation (HTE) techniques. A full-factorial HTE approach was applied in the various stages of the development of the catalysts: the synthesis of the materials, their screening as heterogeneous catalysts in liquid-phase epoxidation and the optimisation of the reaction conditions. Initially, the chemical composition of transition-metal-free oxides was screened, leading to the discovery of gallium oxide as a novel, active and selective epoxidation catalyst. On the basis of these results, the research line was continued with the study of structured porous aluminosilicates, gallosilicates and silica-gallia composites. In general, the gallium-based materials showed the best catalytic performances. This family of materials represents a promising class of heterogeneous catalysts for the sustainable epoxidation of alkenes and offers a valid alternative to the transition-metal heterogeneous catalysts commonly used in epoxidation. High throughput experimentation played an important role in promoting the development of these catalytic systems.
No file

Dates and versions

hal-00757239 , version 1 (26-11-2012)

Identifiers

Cite

Warunee Lueangchaichaweng, Inge Geukens, Annelies Peeters, Benjamin Jarry, Franck Launay, et al.. Transition-Metal-Free Catalysts for the Sustainable Epoxidation of Alkenes: From Discovery to Optimisation by Means of High Throughput Experimentation. Combinatorial Chemistry and High Throughput Screening, 2012, 15, pp.140-151. ⟨10.2174/138620712798868338⟩. ⟨hal-00757239⟩
56 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More