Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients - Sorbonne Université Access content directly
Journal Articles International Journal of Cardiology Year : 2015

Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients

Eloisa Arbustini

Abstract

Heart failure (HF), a major public health burden affecting 2% of industrialized populations, is a syndrome resulting from structural or functional myocardial impairment leading to inadequate cardiac output to meet the body's metabolic demands [1]. Half of HF patients present systolic dysfunction (systolic-HF), also called reduced ejection fraction (HF-REF), a disease related to various causes including idiopathic Dilated Cardiomyopathy (DCM) and Coronary Artery Diseases (CAD) (ischemic-HF). HF is usually a multifactorial disease but the genetic variants contributing to its susceptibility or its severity may be different according to its underlying causes [2] and their identification is only beginning.[...]
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Dates and versions

hal-01143379 , version 1 (17-04-2015)

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Sophie Garnier, Christian Hengstenberg, Nicolas Lamblin, Olivier Dubourg, Pascal de Groote, et al.. Involvement of BAG3 and HSPB7 loci in various etiologies of systolic heart failure: Results of a European collaboration assembling more than 2000 patients. International Journal of Cardiology, 2015, 189, pp.105-107. ⟨10.1016/j.ijcard.2015.04.003⟩. ⟨hal-01143379⟩
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