The present topic emphasizes the parallel development of concepts in social neurosciences and in other domains such as computer science, affective computing, virtual reality development, and even hardware technologies. While several researchers in neurosciences pointed out the necessity to consider naturalistic social cognition (Zaki and Ochsner, 2009), the second person perspective (Schilbach et al., 2013), social interaction (Pfeiffer et al.) and reciprocity (de Bruin et al.), both computer and software developments allowed more and more realistic real-time models of our environment and of virtual humans capable of some interaction with users. A new convergence between scientific disciplines might occur from which it is tricky to predict the outcomes in terms of new concepts, methods, and uses.