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Article Dans Une Revue Comptes Rendus. Chimie Année : 2016

Urolithiasis: What can we learn from a Nature which dysfunctions?

David Portehault

Résumé

Learning from Mother Nature constitutes a major intellectual movement encompassing music, architecture and chemistry. In this contribution, we would like to assess the symmetry and the interface present in pathological calcifications in order to propose a bio-inspired approach. We present an overview on the observations made on kidney stone growth at the macroscopic scale. The results are discussed at the molecular scale and examples are proposed to implement the biological asymmetrical growth in pathological calcifications in biomimetic strategies such as in in vitro microfluidic experiments.
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hal-01305461 , version 1 (21-04-2016)

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Dominique Bazin, David Portehault, Frederik Tielens, Jacques Livage, Christian Bonhomme, et al.. Urolithiasis: What can we learn from a Nature which dysfunctions?. Comptes Rendus. Chimie, 2016, 19 (11-12), pp.1558-1564. ⟨10.1016/j.crci.2016.01.019⟩. ⟨hal-01305461⟩
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